摘要
目的研究常山胡柚（Citrus changshan-huyou Y.B.Chang）的化学成分。方法采用硅胶柱色谱和ODS柱色谱进行分离,以Sephadex LH-20色谱及制备液相色谱进行纯化,根据理化性质和波谱学数据分析鉴定结构。结果分离鉴定了8个已知化合物,分别是圣草次苷（1）、新北美圣草苷（2）、柚皮芸香苷（3）、新橙皮苷（4）、柠檬苦素（5）、胡萝卜苷（6）、β-谷甾醇（7）、蔗糖（8）。结论化合物1~4均为首次从该植物中分离得到。
Aim To study chemical constituents of Citrus changshan-huyou Y.B.Chang.Methods The constituents were firstly separated by column chromatography with silica gel and flash ODS,then purified by Sephadex LH-20 and Pre-HPLC.The structures of these compounds were identified on the basis of physico-chemical properties and spectroscopic data.Results Eight compounds were isolated and identified as eriocitrin（1）,neoeriocitrin（2）,narirutin（3）,neohesperidin（4）,limonin（5）,daucosterol（6）,β-sitosterol（7）,and sucrose（8）.Conclusion Compounds 14 were obtained from Citrus changshan-huyou Y.B.Chang.for the first time.
出处
《中国药物化学杂志》
CAS
CSCD
2010年第2期129-132,共4页
Chinese Journal of Medicinal Chemistry
关键词
常山胡柚
柱色谱法
化学成分
结构鉴定
Citrus changshan-huyou Y.B.Chang
column chromatography
chemical constituents
structural identification
