胰岛素泵治疗新诊断的2型糖尿病临床观察

Newly diagnozed patients with type 2 diabetes mellitus treated by insulin pump.

目的比较胰岛素泵持续皮下输注胰岛素(CSⅡ)与多次皮下注射胰岛素(MSⅡ)治疗新诊断的2型糖尿病的优劣性。方法将69例初诊2型糖尿病患者随机分为CSⅡ和MSⅡ组进行治疗,测量其空腹血糖、餐后2h血糖,记录胰岛素用量及血糖达标时间。结果两组均能显著降低空腹和餐后血糖,CSⅡ组血糖达标时间比MSⅡ组更短,CSⅡ组胰岛素用量比MSⅡ组更少,且CSⅡ组发生低血糖的例数明显少于MSⅡ组。结论胰岛素泵进行胰岛素强化治疗安全、有效、简单、易行,大大缩短了控制高血糖时间,减少了低血糖的发生,是糖尿病强化治疗的较好手段。

Objective To investigate difference between continuous subcutaneous insulin infusion （CSⅡ） and multiple subcutaneous insulin injection （MSⅡ） in newly diagnozed patients with type 2 diabetes mellitus. Methods 69 newly diagnozed patients with type 2 diabetes mellitus were randomly assigned into two groups, which were the CSⅡ group and the MSⅡ group. Empty stomach and blood glucose at the second hour of three postprandial, insulin dose, blood glucose control time were observed. Results Both CSⅡ and MSⅡ could effectively reduce fasting blood glucose and postprandial blood glucose. Compare with the MSⅡ group, the blood glucose control time was shorter, the insulin dose was less and the rate of hypoglycemie episodes was lower in the CSⅡ group. Conclusion Insulin pumping therapy as an intensive care is a safe, effective, simple therapeutic method and could shorten the high blood glucose control time and reduce the rate of hypoglycemic episodes. So it is the better way to intensively treat the diabetes mellitus.