期刊文献+

围绝经期妇女胸腰椎骨折患者骨密度分析 被引量:1

Bone mineral density of thoracolumbar vertebral fracture in postmenopausal women.
下载PDF
导出
摘要 目的探讨由轻创伤引起的围绝经期妇女胸腰椎骨折与骨密度的关系,以期为由骨质疏松引起的胸腰椎骨折提供预防和治疗依据。方法对144例40-58岁由轻创伤引起的胸腰椎骨折女性患者和146例同年龄无骨折史来我院健康检查的女性,用双能X线吸收仪测量左股骨近端骨密度,对数据进行统计分析。结果骨折组骨密度(BMD)明显低于对照组,围绝经期妇女骨质疏松检出率胸腰椎骨折组为34.03%,对照组为12.32%,差异有统计学意义(P<0.05)。结论围绝经期妇女由轻创伤引起的胸腰椎骨折与BMD有密切关系。围绝经期妇女应重视BMD变化,预防椎体骨折的发生。 Objective To explore the correlation between thoracolumbar vertebral fracture following low energy trauma and bone mineral density (BMD) in postmenopausal women, and provide basis for the prevention and treatment of thoracolumbar vertebral fracture with osteoporosis. Methods 144 female patients aged from 40 to 58 years who sustained thoraeolumbar vertebral fracture following low energy trauma and 146 females at similar age without fracture history as control group were studied. DXA (Dual X -ray Absorptiometry) was used to measure BMD in the distal left femoral, then these data were used for statistical analysis. Results Thoracolumbar vertebral fracture group had a significantly lower BMD than control group. The detection rate of osteoporosis(OP) were 34. 03% and 12.32% in thoracolumbar vertebral fracture group and control group, respectively. Conclusion Thoracolumbar vertebral fracture in 40 - 58 aged women caused by low energy injury were closely associated with their BMD. It is necessary to pay more attention to the change of BMD and the prevention of thoraeolumbar vertebral fracture in postmenopausal women.
作者 黎慧萍
出处 《海南医学》 CAS 2010年第8期21-22,共2页 Hainan Medical Journal
关键词 围绝经期 胸腰椎骨折 骨密度 骨质疏松 Postmenopausal period Thoracolumbar vertebral fracture Bone mineral density Osteoporosis
  • 相关文献

参考文献3

二级参考文献20

  • 1Ogawa S,Urano T,Hosoi T,et al.Association of bone mineral density with a polymorphism of the peroxisome proliferator-activated receptor gamma gene:PPARgamma expression in osteoblasts biochem.Biophys Res Commun,1999,260(1):122-126
  • 2Miyao M,Hosoi T,Emi M,et al.Association of bone mineral density with a dinucleotide repeat polymorphism at the calcitonin (CT) locus.J Hum Genet,2000,45(6):346-350
  • 3Taboulet J,Frenkian M,Frendo JL,et al.Calcitonin receptor polymorphism is associated with a decreased fracture risk in post-menopausal women.Hum Mol Genet,1998,7(13):2129-2133
  • 4Eckstein M,Vered I,Ish-Shalom S,et al.Vitamin D and calcium-sensing receptor genotypes in men and premenopausal women with low bone mineral density.Isr Med Assoc J,2002,4(5):340-344
  • 5Takaes I,Speer G,Bajnok E,et al.Lack of association between calcium-sensing receptor gene "A986S"polymorphism and bone mineral density in Hungarian postmenopausal women.Bone,2002,30(6):849-852
  • 6Salamone LM,Cauley JA,Zmuda J,et al.Apolipoprotein E gene polymorphism and bone loss:estrogen status modifies the influence of apolipoprotein E on bone loss.J Bone Miner Res,2000,15:308-314
  • 7Cauley JA,Zmuda JM,Yaffe K,et al .Apolipoprotein E polymorphism:A new genetic marker of hip fracture risk—The study of osteoporotic fractures.J Bone Miner Res ,1999,14(7):1175-1181
  • 8Langdahl BL,Lokke E,Carstens M,et al.Osteoporotie fractures are associated with an 86-base pair repeat polymorphism in the interleukin-1—receptor antagonist gene but not with polymorphisms in the interleukin-1beta gene:J Bone Miner Res,2000,15(3):402-414
  • 9Bajnok E,Takacs I,Vargha P,et al.Lack of association between interleukin-1 receptor antagonist protein gene polymorphism and bone mineral density in hungarian postmenopausal women.Bone,2000,27(4):559-562
  • 10Ota N,Nakajima T,Nakazawa I,et al.A nueleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density.J Hum Genet,2001,46(5):267-272

共引文献1240

同被引文献12

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部