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10日序贯疗法根除幽门螺杆菌的疗效观察 被引量:3

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摘要 目的观察由奥美拉唑联合阿莫西林、克拉霉素及呋喃唑酮组成的10日序贯疗法根除幽门螺杆菌(Hp)的疗效。方法将经胃镜确诊为慢性胃炎伴胃黏膜萎缩或糜烂和胃十二指肠溃疡且Hp阳性患者共90例随机分成治疗组(45例)和对照组(45例),治疗组方案为前5d奥美拉唑+阿莫西林,后5d奥美拉唑+克拉霉素+呋喃唑酮;对照组方案为标准三联疗法(奥美拉唑+阿莫西林+克拉霉素治疗10d)。结果治疗组Hp根除率为93.3%(42例),对照组为73.3%(33例),两组比较差异有统计学意义(p<0.05)。结论以奥美拉唑+阿莫西林+克拉霉素+呋喃唑酮组成的10日序贯疗法根除成人Hp感染疗效较为显著、耐受性好、依从性好。
作者 姜云
出处 《现代实用医学》 2010年第3期307-308,共2页 Modern Practical Medicine
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