酵母菌转化人参皂苷Rb1的动力学

Kinetics bio-transformating ginsenoside Rb1 by yeast

在分批发酵中,对酵母菌转化人参皂苷的动力学进行了研究。应用Logistic方程和Luedeking-Piret方程,得到了描述分批发酵过程中,酵母菌体生长、底物消耗和产物合成的动力学模型及模型参数,并对实验数据与模型进行了验证比较,模型计算值与实验值拟合良好,所建模型能很好地描述酵母菌转化人参皂苷的动力学特征。为进一步研究和预测酵母菌生物转化过程奠定理论基础。

Kinetics of yeast ginsenoside biotransformation was studied.Based on Logistic equation and Luedeking-Piret equation,the kinetic models describing cell growth,product synthesis and substrate consumption were obtained,and the models were approved again to be better correlated with experimental data.The models could well explain to ginsenoside biotransformation by yeast.This result will provide the theoretical foundation for the further study biotransformation process with yeast in future.