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氨酚羟考酮控制中重度癌痛疗效观察 被引量:4

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摘要 目的探讨氨酚羟考酮控制中重度癌痛的疗效。方法将入选病例94例随机分为氨酚羟考酮组和盐酸曲马朵组,氨酚羟考酮组口服氨酚羟考酮片1~2片/次,3/d;盐酸曲马朵组口服盐酸曲马朵片50~100mg/次,3/d,连服5d评价疗效。结果氨酚羟考酮在控制疼痛效果、作用起效时间及改善生活质量方面优于曲马朵,而作用持续时间及不良反应发生率比较,两药无显著差异。结论氨酚羟考酮是控制中重度癌痛的有效药物。
机构地区 解放军
出处 《华北国防医药》 2010年第2期116-117,共2页 Medical Journal of Beijing Military Region
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  • 1视觉模拟评分法[J].中国微侵袭神经外科杂志,2004,9(11):483-483. 被引量:232
  • 2胡红丰,汪红华,方明艳.布洛羟考酮片[J].中国新药杂志,2005,14(11):1362-1363. 被引量:1
  • 3刘艳丽,亓佳,吴春福,宫泽辉.羟考酮精神依赖的形成与纹状体多巴胺释放的关系[J].中国药理学与毒理学杂志,2006,20(1):44-47. 被引量:8
  • 4李俊英,余春华,向秋芬.美施康定治疗癌性疼痛副作用的处理[J].护士进修杂志,2006,21(2):171-173. 被引量:6
  • 5Caldwell J R, Hale M E, Boyd R E. Treatment of osteoarthritis pain with controlled release oxycodone or fixed combination oxycodone plus acetaminophen added to nonsteroidal antiinflammatory drugs: a double blind, randomized, multicenter, placebo controlled trial [ J ]. J Rheumatol, 1999,26 ( 4 ) : 862-869.
  • 6Litkowski L J,Christensen S E,Adamson D N,et al. Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7. 5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain : a randomized, double-blind, placebo-controlled, single-dose ,parallel-group study in a dental pain model[ J]. Clin Ther,2005,27(4) :418-429.
  • 7Malmstrom K, Ang J, Fricke J R, et al. The analgesic effect of etoricoxib relative to that of cetaminophen analgesics: a randomized,controlled single-dose study in acute dental impaction pain[J]. Curr Med Res Opin,2005,21 (1) :141-149.
  • 8Hagen N A,Babul N.Comparative clinical efficacy and safety of a novel controlled-release oxycodone formulation and controlled-release hydromorphone in the treatment of cancer pain[J].Cancer,1997,79 (7):1428-1437.
  • 9Heiskanen T,Kalso E.Controlled-release oxycodone and morphine in cancer related pain[J].Pain,1997,73 (1):37-45.
  • 10Bruera E,Belzile M,Pituskin E,et al.Randomized,doubleblind,cross-over trial comparing safety and efficacy of oral controlled-release oxycodone with controlled-release morphine in patients with cancer pain[J].J Clin Oncol,1998,16(10):3222-3229.

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