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吉西他滨致急性肺水肿1例护理体会 被引量:2

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摘要 吉西他滨是阿糖胞苷类抗代谢抗癌药物。其在体内被转化为双氟脱氧三磷酸胞苷掺人DNA使DNA断裂,从而起到细胞毒作用,为细胞周期特异性药物,主要作用于S期(DNA合成期)和G1期(细胞有丝分裂的第一间歇期),由于其还能抑制脱氧胞嘧啶脱氧酶,减少细胞内代谢药物降解,具有细胞内浓度白增强作用,因而对多种实体瘤有效。
机构地区 河源市人民医院
出处 《基层医学论坛》 2010年第12期373-374,共2页 The Medical Forum
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