孕妇体重指数变化对新生儿体重的影响

Effect of change in antenatal body mass index of neonatal macrosomia on the body mass of newborns

目的:探讨孕妇体重指数变化对新生儿体重的影响。方法:对近2年来我院产检并分娩的447例初产妇的妊娠初期体重指数、妊娠37周后体重指数及其新生儿体重,应用Logistic回归分析评估其与巨大儿的关系。结果:496例产妇中,共有447例用于分析,检出巨大儿56例,检出率为12.5%。与非巨大儿母亲孕期体重指数增量>6者的构成比(90/391,23.0%)相比,巨大儿母亲孕期体重指数增量>6者的构成比(43/56,76.8%)较高(P<0.01)。Logistic回归分析显示,孕期体重指数增量>6是巨大儿的危险因素(RR=11.016,95%CI为5.650～21.477,P<0.01),而年龄和孕次对巨大儿发生率的影响不明显。结论:初产妇孕期体重指数增量>6与巨大儿有关。

Objective：To evaluate the predictive value of change in antenatal maternal body mass index （BMI） and the relationship with macrosomia. Methods：We analyzed data of consecutive deliveries of 447 cases from the recent 2 years in our hospital,focusing on first visit （first trimester） BMI,last visit （37 weeks or later） BMI and fetal birth weight. Logistic regression was used to evaluate the relationship between change in BMI and macrosomia. Results：Of the 496 consecutive deliveries,447 were analyzed,of which 56 （12.5%） of the infants were macrosomic. Among macrosomic infants,76.8% （43/ 56） of their mothers had a more than 6 increase in BMI compared with 23.0% （90/391） of mothers of normal weight infants （P0.01）. Logistic analysis showed that a more than 6 increase in BMI was a risk factor of macrosomia （RR=11.016,95% CI was 5.650-21.477,P0.01）. Age and time of pregnancy had no obvious effect on the incidence rate of macrosomia. Con-clusion：An increase in maternal BMI of more than 6 during pregnancy is highly predictive of macrosomia.