分化型甲状腺癌67例临床分析

Clinical analysis of 67 cases with differentiated thyroid carcinoma

目的探讨分化型甲状腺癌的诊治方法选择。方法回顾性分析我院治疗的67例分化型甲状腺癌临床资料。结果失访12例，复发9例，死亡2例，5年生存率94％，10年生存率89％。结论对分化型甲状腺癌，主张行患侧腺叶加峡部切除及对侧腺叶次全切除。对颈淋巴结阳性，同时行患侧功能性颈淋巴结清扫术；术后行131I治疗者，复发和死亡率明显低于仅行甲状腺激素替代治疗或未行任何治疗者。

Objective To explore the differentiated thyroid cancer diagnosis and treatment options. Methods Clinical data of 67 patients with differentiated thyroid carcinoma from 1996 to 2008 were reviewed ret- rospectively. Results 12 cases lost follow-up, 9 cases recurred, 2 cases died, the 5-year and 10-year survival rate were 94% and 89%. Conclusions Excision of the tumor located lobe, isthmus and subtotal lobectomy for the contralateral lobe is appropriate for differentiated thyroid carcinoma. Tumor ipsilateral side functional cervical dissection is appropriate for patients with cervical lymph node metastasis. 131I treatment can significantly lower the recurrence and mortality compare to those patients only treated with thyroid hormones replacement or without any treatment after poeration.