高血压患者糖代谢状态及其相关因素探论

Status of glucose metabolism in patients with hypertension and its related factors on exploration

目的:探讨高血压患者糖代谢状态及其相关因素。方法:167例高血压患者晚餐后禁食12～14h,次日清晨抽血,分别测定血糖、TC、TG、HDL-C和LDL-C,并完成血压、体脂参数等测定。结果:本研究中高血压患者糖代谢异常的发生率高达68.3%。在对高血压患者不同糖代谢状态所占数目及其构成比的研究中,DM组、IFG组和IGT组的男女数目经统计,P<0.05,差异有统计学意义,不同年龄段高血压患者糖代谢异常组例数的分布情况看,46～55岁和56～65岁两个年龄段的数目比例较高;Logistic回归分析显示年龄、性别、饮酒、肥胖、T2DM家族史、高血压病程、BMI、血脂与高血压患者糖代谢异常的发生独立正相关。结论:高血压患者合并糖代谢异常较常见;男性患者更易发生糖代谢异常;性别、年龄、饮酒、原发性高血压病(EH)家族史、T2DM家族史、EH病程长、高收缩压、高血脂是糖耐量正常EH患者发生糖代谢异常的独立危险因素。一旦怀疑,应积极干预,及时进行危险因素评估。

Objective：To investigate the status of glucose metabolism in patients with hypertension and its related factors.Methods：167 patients with hypertension after dinner fasted 12-14 h,the next morning a blood sample,blood glucose were measured,TC,TG,HDL-C and LDL-C.And complete blood pressure,body fat parameters measured.Results：In this study,abnormal glucose metabolism in patients with hypertension incidence rate of 68.3%.In hypertensive patients with different status of glucose metabolism in the number and composition ratio of share of the study,DM group,IFG group and IGT group the number of men and women through the statistics,P0.05,with a significant difference;glucose in hypertensive patients of different ages metabolic disorders group distribution of the number of cases of view,46-55 and 56-65 years old group the number of two high proportion;Logistic regression analysis showed that age,sex,drinking,obesity,T 2DM family history,hypertension duration,BMI,blood lipids and hypertension incidence in patients with abnormal glucose metabolism independent positive correlation.Conclusion：The abnormal glucose metabolism in patients with hypertension more common;male patients more likely to have abnormal glucose metabolism;sex,age,alcohol consumption,EH family history,T2DM family history,EH longer duration,high systolic blood pressure,high cholesterol is a normal glucose tolerance EH oc curred in patients with abnormal glucose metabolism independent risk factors.Once the suspect should actively intervene timely assessment of risk factors.