^(18)F-FDG PET-CT诊断乳腺癌骨转移的临床应用

Clinical application of ^(18)F-FDG PET-CT for Detecting Bone Metastasis of Breast Carcinoma

目的:分析18F-FDG PET-CT对乳腺癌骨转移的诊断价值。材料与方法:对107例乳腺癌患者静脉注射18F-FDG行全身PET-CT显像。结果:107例中发现骨转移22例,阳性率20.6%,其中无骨痛患者发生骨转移4例;单发转移9例;多发转移13例。发现骨转移灶的部位依次为胸廓(61处)、骨盆(41处)、脊柱(39处)、四肢(8处)及头颅(4处)。随乳腺癌术后回访年限的增加,骨转移阳性率增加。结论:18F-FDG PET-CT可早期诊断乳腺癌骨转移,对于病情评价及制定治疗方案有重要的指导意义。

Purpose： To analyze the diagnostic value of PET - CT for skeletal metastsis of breast carcinoma. Materi- Ms and Methods： 107 patients with breast carcinoma were injected intravenously 18F- FDG and examined the whole body. Results： In the breast carcinoma patients, 22 cases were discovered metastases tumor in bones and the positive rate was 20. 6%, in whom 4 were pain - free metastasis. Single metastasis were found in 9 cases and muhimetastase in 13. Region and number of the bone metastasis were as follows： ribs（61）, pelvis（41 ）, spinal column（39）, arms and legs（8）and skull （4）. The skeletal metastasis rate was increased along with the prolongation of the follow - up period. Conclusion： PET - CT is eligible for finding the skeletal metastasis at early time. Regular follow - up is necessary for securing a right assessment of the illness and for establishing the proper treatment protocols