由日本萍蓬草提取的抗醋霉菌果蝇的杀虫生物碱
被引量：1
摘要
在新的天然杀虫活性化合物的研究中,Mitsuo Miyazawa等选择了一些中国天然草药,它们一直被作为医药使用,且安全可靠。在这个由中草药筛选新颖天然杀虫剂的过程中,发现日本萍蓬草根茎的甲醇提取物中存在着抗醋霉菌果蝇(黄猩猩果蝇)幼虫的杀虫活性物质。从该植物中得到的(-)-7-epi-去氧萍蓬汀被证实是颇具潜力的杀虫化合物。 日本萍蓬草是一种在北半球温带广泛分布的多年生根状茎的草科植物。
同被引文献53
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1章灵华,黄艺,钱玉昆,肖培根.去氧萍蓬草碱在体外对免疫功能的影响[J].中国医学科学院学报,1995,17(5):343-348. 被引量：4
-
2Yoshikawa M, Murakami T, Wakao S, et al. Crude drugs from aquatic plants. VI1 On the alkaloid constituents of Chinese Nupharis rhizoma, The dried rhizoma of Nuphar pumilum (Timm.) De. (nymphaceae): Structures and rearrangement reaction of thiohemiaminal type Nuphar alkaloids [J]. Heterocycles, 1997, 45(9): 1815-1824.
-
3Matsuda H, Shimoda H, Yoshikawa M. Dimeric sesquiterpene thioalkaloids with potent immuno- suppressive activity from the rhizome of Nuphar pumilum: Structural requirements of Nuphar alkaloids for immunosuppressive activity [J]. Bioorg Med Chem, 2001, 9: 1031-1035.
-
4Matsuda H, Morikawa T, Yoshikawa M, et al. Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum [J]. Bioorg Med Chem Lett, 2003, 13: 4445-4449.
-
5Arata Y, Yasuda S, Yamanouchi K. Constituents of rhizoma Nupharis. XXW.I) Formation of dehydro- deoxynupharidine from nupharidine2) [J]. Chem Pharm Bull, 1968, 16(10): 2074-2077.
-
6La Londe R T, Wong C F, Woolever J T, et al. Electron-impact mass spectrometry of Nuphar alkaloids [J]. OrgMass Spectrom, 1974, 9: 714-725.
-
7Itatani Y, Yasuda S, Hanaoka M, et al. Constituents of rhizoma Nupharis. XXVI. Carbon-13 nuclear magnetic resonance spectra of nupharamine, anhydronupharamine, nuphamine, and related compounds [J]. Chem Pharm Bull, 1976, 24(10): 2521-2524.
-
8Kogure N, Nozoe A, Kitajima M, et al. Nupharic acid, A new sesquiterpene alkaloid from Nuphar japonicum [J]. Heterocycles, 2009, 79:1101-1105.
-
9Wrobel J T. The Alkaloids [M]. New York: Academic Press, 1967.
-
10Valenta Z, Khaleque A. The structure of castoramine [J]. Tetrahedron Lett, 1959, 12: 1-5.
