摘要
经颈静脉肝内门体分流术（TIPS）是治疗门静脉高压症的有效手术之一。本文提出了一个集中参数模型对TIPS进行血液动力学分析。首先根据门脉高压的前向血流学说和后向血流学说，计算了门静脉系统血液动力学参数，然后计算了TIPS术后门静脉系统血液动力学参数的变化，并详细分析讨论了这些血液动力学参数随肝硬变梗阻程度的变化，以及TIPS分流道阻力对它们的影响。结果表明所得结果和临床所测参数吻合较好，该模型可进一步应用于门脉高压症和其它分流术血液动力学机理研究，并为临床应用提供参考。
Transjuguler Intrahepatic Portosystemic Shunt (TIPS) is one of effective surgeries for portal hypertension. A lumped parameter mathematical model of the splanchnic circulation was presented to study TIPS hemodynamics. Firstly the hemodynamics parameters of portal Hypertension were calculated according to both Back word Mechanism and Forword Mechanism. Then the hemody nanmics parameters of portal system after TIPS were calculated. The variation of these hemodynamics parameters with cirrhosis and effection of TIPS shunt resistance on it were analysised. It is shown that the results were accord with clinical measurement, and the model presented in this paper can be applied to hemodynamics mechanism study of portal hypertension and other shunt surgeries,and can supply information for clinical application.
出处
《医用生物力学》
EI
CAS
CSCD
1998年第3期140-146,共7页
Journal of Medical Biomechanics
基金
国家自然科学基金!19572026
