兔股动、静脉裂隙宽度与实际缺损长度的关系

THE RELATIONSHIP BETWEEN GAP WIDTH(GW) AND ACTUAL DEFECT LENGTH(ADL) OF FEMORAL ARTERY AND VEIN IN RABBIT MODELS

目的：探讨兔股动、静脉裂隙宽度（GapWidth，GW）与实际缺损长度（ActualDe-feetLength，ADL）二者的关系。方法：游离组：12只兔股动脉、静脉各24条，随机平均分为3组，分别将动、静脉游离15．0mm、25．0mm、35．0mm后锐性横断，测量表观游离长度（ApparentIsolatedLengthApIL），游离长度增大值（IncreasedIsolatedLengthIIL）及裂隙宽度GW的变化，并计算伸长率λ。缺损组：9只兔股动、静脉各18条，实际游离长度（ActualIsolatedLength.AcIL）均为350mm，随机平均分为3组，分别切除动、静脉生理状态下的长度ADL5．0mm、15.0mm、25．0mm。测量ApIL、IIL及GW。结果：单纯横断股动静脉，IIL及λ不受AcIL的影响（P＞0．05），GW随AcIL的增长呈线性增长：ΔGW=ΔAcIL（1－1／λ）;AcIL一定时，ADL对IIL及ApIL无影响（P＞0．05），GW随ADL的增大呈线性增长：ΔGW=ΔADL·1／λ。结论：兔股动、静脉在AcIL≤35．0mm时，ADL.ApIL．AcIL.IIL.GW之间存在线性关系：ADL=AcIL－（AcIL＋IIL－GW）·λ或ADL=（ApIL－IIL）－（ApIL－GW）·λ（λa=1.58），λv=1．64，IILa=3．85mm，IILv＝3．39mm）。

Objective:To investigate the relationship between gap width(GW) and actual defect length(ADL) of femoral artery and vein. Methods:The influence of actual isolated length(ACIL) on GW was investigated in section A. Twenty-four femoral arteries (veins) in 12 rabbits were randomly divided into three groups. A range of 15.0mm, 25.0mm and 35.0mm of artery(vein) was isolated from peri-vascular connective tissues(including femoral nerve and vein) and arterial (venous) brallches respectively to clear off longitudinal vascular tedlering in different groups. Apparent isolated lengh (ApIL), increased isolated lengal (IIL) and GW were measured after the artery was transected at its middle portion and stretch ratio(λ) was caculated. The influence of ADL on GW was investigated in section B. Eighteen femoral arteries (veins) in nine rabbits were randomly divided into three groups (AcIL=35.00mm). A segment of 5.0mm, 15.0mm and 25.0mm long arteries (veins) at physiological tension was resected respectively. ApIL. IIL and GW were measured. Results:IIL and λ were unchallgeable while a linear relationship existed between GW and AcIL (GW=AcIL· (1 -1/λ) in statistics in section A. In section B, ADL didn't influence ApIL and IIL but increased GW linealy (ΔGW=ΔADL/λ) in statistics. Conclusion: An adaptive relationship may exist between GW, AcIL and ADL within 35.0mm AcIL range of rabbit's femoral vessel: ADL=AcIL- (AcIL+IIL- GW)·λ orADL= (ApIL-IIL)-(ApIL - GW)·λ. (λa=1.58, λv = 1.64, IILa= 3.85mm, IILv= 3.39mm).