依沙吖啶联合米非司酮用于剖宫产术后疤痕子宫引产疗效观察

Clinic effect of combination of ethacridine and mifepristone on induced labor for pregnancy with cicatricial uterine due to caesarean section

目的:观察依沙吖啶羊膜腔内注射配伍米非司酮口服用于剖宫产术后疤痕子宫引产的临床效果。方法:将200例中期妊娠要求引产的疤痕子宫妇女分为观察组(100例)与对照组(100例),观察组在依沙吖啶羊膜腔内注射引产当日口服米非司酮150mg;对照组常规进行依沙吖啶羊膜腔内注射引产。结果:观察组与对照组引产成功率、产后出血量,比较差异无统计学意义(P>0.05);引产时间、胎盘、胎膜残留情况,胎盘粘连发生率,差异有统计学意义(P<0.05)。结论:依沙吖啶联合米非司酮用于疤痕子宫引产可明显缩短引产时间,减少并发症的发生,是一种理想、安全、有效的引产方法。

Objective：To observe the effect of amniotic cavity injection with ethacridine and oral administration of mifepristoneon on induced labor for pregnancy with cicatricial uterine due to caesarean section.Methods：Randomly divided 200 second trimester pregnancy women with cicatricial uterine into observation group（100 cases）and control group（100 cases）.Treated observation group with amniotic cavity injection of ethacridine and oral administration of 150 mg mifepristoneon,while treated control group with only ethacridine injection.Results：There was no significantly difference in success rate of induced labor,postpartum bleeding volumn between two groups（P〉0.05）,while the delivering time,residue status of placenta and fetus membrane in observation group significantly differed from control group（P〈0.05）.Conclusion：Combined application of ethacridine and mifepristone can markedly shorten delivery time,reduce the occurrence of complication.It is safe and effective.