复可托与左旋咪唑防治小儿反复呼吸道感染疗效比较

Effects comparison of fuketuo and levamisole on recurrent respiratory tract infection in children

目的:比较复可托与左旋咪唑防治小儿反复呼吸道感染的疗效。方法:96例临床诊断的反复呼吸道感染的患儿随机分为复可托组与左旋咪唑组,各48例。复可托组采用复可托(脾氨肽口服冻干粉)每晚1支,3周后每周服2支,总疗程2～3个月;左旋咪唑组每周1,2,3用药3d,用量1.5mg·kg-1.d-1,疗程2～3个月。观察两组小儿反复呼吸道感染疗效及不良反应。结果:复可托组有效率为91.7%,不良反应率为12.5%;左旋咪唑组有效率为54.2%,不良反应率为2.1%,两组比较差异有统计学意义(P<0.01)。结论:复可托防治小儿反复呼吸道感染疗效满意,不良反应小,安全可靠,值得临床推广应用。

Objective：To compare the effects of fuketuo and levamisole on recurrent respiratory tract infection in children.Methods：A total of 96 respiratory tract infection cases were randomly divided into fuketuo group and levamisole group by half.The former was treated with one dose of oral fuketuo every night,3 weeks later increasing to 2 does for a continuous 2-3 months course.The latter group was treated with levamisole on Monday,Tuesday and Wednesday of each week,1.5 mg/（kg.d）for 2-3 months.The therapeutic effects and side effects of these two groups were observed and compared.Results：The effective rate and side effective rate of fuketuo was 91.7% and 12.5% respectively;for levamisole group,the corresponding rate was 54.2% and 2.1%,showing significant differences between them.Conclusion：With few side effects and satisfactory treatment effects,fuketuo is effective on recurrent respiratory tract infections in children.