临床真菌分离及药敏分析

Isolation and antimicrobial susceptibility of clinical fungal

目的了解某院临床真菌分离及药敏情况。方法各种标本经常规方法分离培养，用法国生物梅里埃公司的VITEK23鉴定系统鉴定，并用K-B法进行药敏试验。结果临床标本中分离出真菌239株，以白色念珠菌为主（174株），占72．8％；其次克柔念珠菌（44株），占18．4％；热带念珠菌（21株），占8．8％。各种真菌对8种抗真菌药物呈现出不同的敏感性。结论真菌引起的感染呈逐年上升趋势，重视真菌药敏监测，以指导临床合理选用抗真菌药物。

Objective To understand the clinical fungi in a hospital isolation and drug sensitivity. Methods of specimens isolated and cultured by conventional methods, using the French company＇s VITEK23 bioMerieux identification system identification, and susceptibility testing using KB method. Results Clinical specimens isolated 239 fungi, mainly Candida albicans （174）, accounting for 72.8%; followed by Candida krusei （44）, accounting for 18.4%; Candida tropicalis （21）, accounting for 8.8%. A variety of fungi on the eight kinds of antifungal agents showed different sensitivity. Conclusions Fungal infection was caused by a rising trend year by year, attach importance to monitoring of fungal susceptibility to guide the rational selection of clinical antifungal drug.