慢性疼痛与脑功能磁共振成像及疼痛治疗

Chronic pain and functional magnetic resonance imaging of brain and pain treatment

慢性疼痛时中枢的传导及中枢敏感化可引起脑功能区的生理、病理、脑化学物质、脑的结构、脑的疼痛认知、记忆功能区的变化。此将导致脑功能磁共振成像改变，这种成像改变为我们疼痛诊疗提供了依据。在脑功能磁共振成像引导下，对于急性疼痛治疗强调局部周围神经镇痛治疗时，需辅助疼痛神经组织的脑中枢保护；对于慢性疼痛治疗需进行强化疼痛神经组织的脑中枢保护和疼痛认知、记忆的治疗，直致脑功能磁共振成像的“治愈”。

Central transfer of chronic pain and central sensitization in the brain may result in physiological and pathological ehanges in brain chemicals, structures, perception, and memory function,as a result of inducing the changes of brain functional magnetic resonance imaging, which provide a basis of clinical pain treatment. Under the guidance of brain functional magnetic resonance imaging, local treatment of peripheral nerve pain is stressed for acute pain. The protection of brain center is required for the treatment of chronic pain, in need of strengthened protection of central nervous tissue of the brain and pain perception, the treatment of memory, until showing of ＂cure＂ in functional magnetic resonance imaging.