羊膜联合Ahmed青光眼减压阀植入术治疗新生血管性青光眼的疗效

Observation on the effect of biological amnion combined with Ahmed glaucoma valve implantation on neovascular glaucoma

目的:观察羊膜联合Ahmed青光眼减压阀植入术在治疗新生血管性青光眼的疗效和并发症。方法:2008-01/2009-09行羊膜联合Ahmed青光眼减压阀植入术25例25眼和单纯Ahmed青光眼减压阀植入术23例23眼的年龄和病因基本匹配的两组患者进行回顾性比较分析。结果:羊膜联合Ahmed青光眼减压阀植入术组出院时成功率96%,术后3mo成功率88%,术后12mo成功率83%。单纯Ahmed青光眼减压阀植入术组出院时成功率91%,术后3mo成功率59%,术后12mo成功率55%。两组中远期效果比较经过χ2检验差异有统计学意义(P<0.05)。结论:羊膜联合Ahmed青光眼减压阀植入术能较安全、有效的治疗新生血管性青光眼,特别是在中远期疗效上优于单纯减压阀植入术。

AIM： To observe the long-term effect and complication of biological amnion combined with Ahmed glaucoma valve implanta-tion on neovascular glaucoma. METHODS： This was a retrospective observational case series. Patients with neovascular glaucoma underwent either of the two procedures from Jan. 2008 Sept. 2009. Twenty-five cases 25 eyes underwent biological amnion combined with Ahmed glaucoma valve implan-tation,while twenty-three cases 23 eyes underwent Ahmed glaucoma valve implantation. RESULTS： The success rate of biological amnion combined with Ahmed glaucoma valve implantation was 96% at the time of discharge from hospital and 88% 3 months later, 83% 12 months later; while the rate of Ahmed glaucoma valve implantation were 91% at the time of discharge from hospital and 59% 3 months later, 55% 12 months later. The long-term effects of the two groups had statistical difference （P〈0.05）. CONCLUSION： It is considered the biological amnion combined with Ahmed glaucoma valve implantation surgery may be effective and safe for treating neovascular glaucoma .