期刊文献+

Graves病患者在甲巯咪唑治疗前后血清CXCL10的变化 被引量:2

下载PDF
导出
摘要 Graves病(GD)是一种常见的自身免疫性甲状腺疾病(AITD),其发病率约1%~2%,近年来呈逐年增高趋势。GD的特点是甲状腺内弥漫性淋巴细胞浸润,浸润程度随疾病类型和病程发生变化。CXC亚族趋化因子CXCL10具有趋化T淋巴细胞等炎细胞浸润、增殖,介导抗体特异性的自身免疫反应的作用,在GD初期发挥重要作用。
出处 《天津医药》 CAS 北大核心 2010年第3期235-236,共2页 Tianjin Medical Journal
  • 相关文献

参考文献7

  • 1黄勤.格雷夫斯病的治疗进展[J].新医学,2000,31(8):491-491. 被引量:3
  • 2Romagnani P,Rotondi M,Lazzeri E,et al.Expression of CXCL10/CX CL10 and MIG/CXCL9 in the thyroid an d increased levels of IP10/CXCLIO in the serum of patients with recent-onset Graves disease[J].Am J Pathol,2002,161(1):195-206.
  • 3Antonelli A,Fallahi P,Rotondi M,et al.Increased serum CXCL10 in Graves' disease or autoimmune thyroiditis is not associated with hyper-or hypothyroidism perse,but is specifically sustained by the autoimmune,inflammatory process[J].Eur J Endocrinol,2006,154(5):651-658.
  • 4Crescioli C,Cesmi L,Borgogni E,et al.Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes[J].J Endocrinol,2007,195(1):145-155.
  • 5Weetman AP.Autoimmune thyroid disease:propagation and progression[J].Eur J Endocrinol,2003,148(1):1-9.
  • 6Antonelli A,Fallahi P.Serum levels of the interferon-gamma-inducible alpha chemokine CXCL10 in patients with active Graves'disease,and modulation bymethimazole therapy and thyroidectomy[J].Br J Surg,2006,93(10):1226-1231.
  • 7Gianoukakis AG,Douglas RS,King CS,et al.Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes:a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease[J].Endocrinology,2006,147(4):1941-1949.

二级参考文献2

共引文献2

同被引文献11

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部