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肿瘤相关性视网膜病变的研究进展 被引量：1

Recent advances on cancer-associated retinopathy
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摘要 肿瘤相关性视网膜病变(cancer-associated retinopathy,CAR)是一种与肿瘤有关的视网膜变性疾病,其发病机制认为是肿瘤抗原诱导机体产生抗视网膜蛋白的抗体而引起的自身免疫性疾病,而非眼部原发肿瘤的占位压迫或全身其他部位肿瘤转移所引起。CAR对视功能的影响很大,目前该病已逐渐被眼科医师所认识。本文从CAR的发病机制、临床表现、诊断及鉴别诊断、治疗方面作一综述。 Cancer-associated retinopathy（CAR）is a degenerative disease related to cancer.It is considered to be an autoimmune disorder that involves tumor antigen inducing body to produce antibody to resist retinal protein,not caused by oppression of ocular primary tumor or metastasis from tumor in other parts of body.Visual function is damaged seriously in CAR patients.At present,the disease has gradually been recognized by ophthalmologist.This paper reviews pathogenesis,clinical manifestations,diagnosis,differential diagnosis and treatment of CAR.
作者 孙荣 陈长征 郑红梅 邢怡桥
机构地区 武汉大学人民医院眼科
出处 《眼科新进展》 CAS 北大核心 2010年第4期390-392,共3页 Recent Advances in Ophthalmology
关键词 肿瘤相关性视网膜病变 视网膜抗原 自身抗体 视功能障碍 cancer-associated retinopathy retinal antigen autoantibody visual disorder
分类号 R777.2 [医药卫生—眼科]
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参考文献25

  • 1Sawyer RA, Selhorst JB, Zimmerman LE, Hoyt WF. Blindness caused by photoreceptor degeneration as a remote effect of cancer[ J]. Am J Ophthalmol, 1976,81 ( 5 ) :606-613.
  • 2刘娅利,张军军.癌症相关性视网膜病变的自身免疫机制[J].中华眼底病杂志,2004,20(4):267-269. 被引量：4
  • 3Ohguro H, Yokoi Y, Ohguro I, Mamiya K, Ishikawa F, Yamazaki H,et al. Clinical and immunologic aspects of cancer associated retinopathy[ J ]. Am J Ophthalmol,2004,137 ( 6 ) : 1117-1119.
  • 4Bazhin AV, Schadendorf D, Philippov PP, Eiclunuller SB. Recoverin as a cancer-retina antigen [ J ]. Cancer Immunol Immunother,2007,56 ( 1 ) : 110-116.
  • 5Marinkovic M ,van Lanschot J J, Schlingemann RO, de Smet MD, Saeed P. Eye complaints indicative of a tumor elsewhere in the body[ J]. Ned Tijdsch, r Geneeskd ,2002,146 ( 50 ) :2393-2396.
  • 6Chan JW. Paraneoplastic retinopathies and optic neuropathies [ J ]. Sure Ophthalmol,2003,48 ( 1 ) : 12-38.
  • 7Ohguro H, Maruyama I, Nakazawa M, Oohira A. Antirecoverin antibody in the aqueous humor of a patient with cancer-associated retinopathy [ J ]. Am J Ophthalmol, 2002,134 ( 4 ) : 605-607.
  • 8Saito W, Kase S, Ohquro H, Furudate N, Ohno S. Slowly progressive cancer-associated retinopathy [ J ]. Arch Ophthalmol, 2007, 125(10) :1431-1433.
  • 9Bidegain C, Rigalt J, Ribot E, Dorca J, Vayreda J. Small cell lung cancer and cancer-associated retinopathy [ J ]. Arch Bronconeumol,2005,41 (2) :99-101.
  • 10Katsuta H, Okada M, Nakauchi T, Takahashi Y, Yamao S, Uchida S. Cancer-associated retinopathy with invasive thymoma [ J ].Am J Ophthalmol,2002,134 ( 3 ) : 383-389.

二级参考文献47

  • 1王雨生,严密,惠延年.癌症相关性视网膜病变[J].中华眼底病杂志,1997,13(1):60-62. 被引量：4
  • 2大黑 浩 丸山畿代 中(氵尺)满.A case of AZOOR by rod photoreeeptor dysfunction[J].眼科,2002,44:239-242.
  • 3松本泰明 福岛伊知郎 松原孝 等.Systemic corticosteriod was effective in a case of AZOOR[J].临床眼科,2002,56(1):63-67.
  • 4Gass JD. Acute zonal occult outer retinopathy. Donders Lecture:The Netherlands Ophthalmological Society, Maastricht, Holland,June 19, 1992. J Clin Neuroophthalmol, 1993, 13 (2): 79--97.
  • 5Jacohson SG, Morales DS, Sun XK, et al. Pattern of retinal dysfunction in acute zonal occult outer retinopathy. Ophthalmology, 1995, 102 (8): 1187--1198.
  • 6Gass JD, Agarwal A, Scott IU. Acute zonal occult outer retinopathy: a long- term follow - up study. Am J Ophthalmol,2002, 134 (3): 329-339.
  • 7Smetana S, Feman SS, Kleber C. The retinal features of acute zonal occult outer retinopathy (AZOOR). Arch Ophthalmol,2003, 121 (6): 914--915.
  • 8Holz FG, Kim RY, Schwartz SD, et al. Acute zonal occult outer retinopathy (AZOOR) associated with multifocal choroidopathy. Eye, 1994, 8 (Pt 1): 77--83.
  • 9Helbig H, Sutter F, Tholen A. Acute zonal occult outer retinolmthy (AZOOR). Ophthalmologe, 2001, 98 (6): 574--578.
  • 10Al - Yousuf N, Parks S, Dhillon B, et al. Acute zonal occult outer retinopathy. Br J Ophthalmol, 2000, 84 (1) : 118-- 119.

共引文献6

同被引文献38

  • 1刘娅利,张军军.癌症相关性视网膜病变的自身免疫机制[J].中华眼底病杂志,2004,20(4):267-269. 被引量：4
  • 2王雨生,严密,惠延年.癌症相关性视网膜病变[J].中华眼底病杂志,1997,13(1):60-62. 被引量：4
  • 3Sawyer RA, Selhorst JB, Zimmerman LE, et al. Blindness caused by photoreceptor degeneration as a remote effect of cancer. Am J Ophthalmol, 1976,81:606-613.
  • 4Gass J. Acute Vogt-Koyanagi-Harada-like syndrome occurring in a patient with metastatic cutaneous melanoma//Saari K. Uveitis Update: Proceedings of the First International Symposium on Uveitis. Amsterdam, the Netherlands : Elsevier Science, 1984 : 407 -408.
  • 5Adamus G. Autoantibody targets and their cancer relationship in the pathogenicity of paraneoplastic retinopathy. Autoimmun Rev, 2009,8:410-414.
  • 6Khan N, Huang JJ, Foster CS. Cancer associated retinopathy (CAR) :an autoimmune-mediated paraneoplastic syndrome. Semin Ophthalmo1,2006,21 : 135-141.
  • 7Kondo M, Mokuno K, Uemura A, et al. Paraneoplastic retinopathy associated with retroperitoneal liposarcoma. Clin Ophthalmol, 2010,4:243-245.
  • 8Adamus G, Machnicki M, Seigel GM. Apoptotic retinal cell death induced 'by antirecoverin autoantibodies of cancer-associated retinopathy. Invest Ophthalmol Vis Sci, 1997,38:283-291.
  • 9Lei B, Bush RA, Milam AH, et al. Human melanoma-associated retinopathy(MAR) antibodies alter the retinal ON-response of the monkey ERG in vivo. Invest Ophthalmol Vis Sci, 2000,41 : 262- 266.
  • 10Thirkill CE, Roth AM, Keltner JL. Cancer-associated retinopathy. Arch Ophthalmol, 1987,105:372-375.

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眼科新进展
2010年 第4期

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