PASS监测用药风险警示的评估及成因分析

Factor Analyse and Risk Vigilance Evaluate of PASS Used Monitoring Prescription

目的了解PASS监测系统在临床治疗中的警示作用并进行溯源评估。方法采用病例观察方法,通过PASS系统对2008年5～12月间3所医院科室的住院医嘱进行监测,评价警示信息有效性并作关联性因素分析。采用SPSS软件进行数据统计分析。结果4910例患者的29700条医嘱中,重点警示信息2813条,主要集中于药物相互作用、特殊人群、配伍禁忌、给药剂量、给药途径;其中有效的1161条信息的关联性因素以人员因素为最多;无效的1652条则主要源自PASS的局限性。结论PASS因其智能化有限,临床存在闯关提交医嘱现象;但用于临床短时大量医嘱的快速初审人工无法替代,其警示信息对于提示临床医师预见并规避可能的风险隐患方面有显著的实用意义。

Objective Analying of influence factor and evaluating of vigilance effection of PASS used monitoring prescription.Methods Using case investigating method.Screenning some inpatient prescription of three hospital during May to December in 2008 by PASS,Evaluating vigilance effection and analyse influence factor.The correlative data were deal with the SPSS software.Results There were 2 813 piece of stress vigilance information in 29 700 prescription of 4 910 cases,Concentrated in five representation-interaction,special patient,no-no mix,dosage and approach.Effective 1 161 piece by reason of personnel,and the other 1 652 piece are restricted by PASS itself.Conclusion Using PASS to monitor prescription have distinct practicality for rational drug use.Its vigilance information can remind doctor to avoid the risk about drug safety.