56例肝胆外科病房深部真菌感染临床分析及防治措施

The clinical analysis of 56 cases with deep fungus infection in hepatobiliary surgical ward and precaution measures of infection

目的探讨肝胆外科病房深部真菌感染的危险因素及防治措施。方法回顾性分析2000年1月至2008年l2月期间肝胆外科病房深部真菌感染56例患者的临床资料。结果56例共分离出66株真菌,深部真菌感染以白色念珠菌居首位,占68.18%,二种以上真菌混合感染者为10.71%。深部真菌感染的疾病主要有重症急性胰腺炎、肝胆胰恶性肿瘤。长期的广谱抗生素及皮质类固醇激素的使用等是真菌感染高危因素。结论深部真菌感染是肝胆外科病房常见的并发症,需及时合理手术、合理使用抗生素,警惕深部真菌感染,做到早期诊断,及时治疗。

Objective To explore the risk factors and precautions of the deep fungus infection in hepatobiliary surgical ward.MethodsClinical date of 56 patients who got deep fungus infeclion in hepatobiliary surgical ward from Janurary 2000 to December 2008 were analyzed retrospectirely.Results66 strains of fungus were separated form 56 specimens and the main was candida albiccans acounting for 68.18%.The mired fungi infection rate with more than two kinds of fungus was 10.71%.The main diseases to led deep fungus infection were severe acute pancreatitis,hepatobiliary and pancreatic carcinoma.Long broad-spectrum antibiotic and corticosteroid use etc were higt risk factors of deep fungus infection.ConclusionThe deep fungus infection is a common complication in hepatobiliary surgical.Ward.We should use the antibiotics resonablely,do the operalions timely to prevent the deep funyus infection.