提高红曲色素水溶性的方法研究

Improving Water Solubility of Monascus Pigment

为提高红曲色素的水溶性,拓宽其应用范围,研究了提高其亲水性的技术方法。选用海藻酸钠水溶液和红曲色素乙醇提取液,将两者按比例混溶,加热回流一定时间,使两种化合物分子间发生反应,从而改善红曲色素的水溶性。通过单因素条件试验和正交试验确定了最适工艺条件:海藻酸钠水溶液质量浓度为4.0 mg/mL,红曲色素乙醇提取液和海藻酸钠水溶液混合体积比为15:5,回流温度60℃,回流时间为40 min。以红外光谱法证实了红曲色素与海藻酸钠有分子间缔合,从而提高了红曲色素的水溶性。

The technic of improving the water solubility of mo （ monascus pigment） to plication was studied. Sodium alginate water solution was mixed with monascouruarin ethanol solution widen its apprepared by GB4926--1985 method, and the mixed solution was refluxing heated for molecular association. Results： The optimal conditions determined with single factor test and orthogonal test are concentration of sodium alginate water solution 4.0 mg/mL, mixing ratio of monascouruarin ethanol solution to sodium alginate water solution 15 ： 5 mL, refluxing temperature was verified 60 ℃ and refluxing time 40 min. The molecular association between monascouruarin and sodium alginate by infra- red spectrometry.