年龄因素对外科治疗肾上腺增生性高血压疗效的影响

Effect of Age Factor on Surgical Treatment of Adrenal Hyperplasia Hypertension

目的对比不同年龄段肾上腺增生患者术后高血压恢复情况,探讨年龄因素对外科治疗肾上腺增生性高血压疗效的影响。方法选取2001—2008年我院行单侧肾上腺切除术治疗肾上腺增生性高血压的患者145例为研究对象,以年龄为分组因素,将患者分为青年组(<45岁)、中年组(45～64岁)和老年组(>64岁),随访患者血压情况,以血压改善情况为指标,行组间对比。结果随访6个月,不同年龄段肾上腺增生性高血压患者术后疗效比较,差异有统计学意义(χ2=8.097,P<0.05)。根据平均秩次进一步推断,青年组术后疗效最好,中年组次之,老年组最差。结论年龄因素对外科治疗肾上腺增生性高血压疗效有影响。

Objective To compare hypertension recoveries in adrenal hyperplasia patients at different ages after operation,to explore the effect of age factors on adrenal hyperplasia hypertension.Methods One hundred forty-five adrenal hyperplasia hypertension patients treated by unilateral adrenalectomy were divided into groups young （〈45 years old）,middle-aged （45～64 years old） and elderly （〉64 years old）.Taking blood pressure improvement as indicators,blood pressure was compared between 3 groups.Results There was significant difference in treatment effectiveness between 3 groups after 6 months of follow up （χ2=8.097,P〈0.05）.Based on the average rank,it was further concluded that the effectiveness was the best in young group,the second best in middle-aged,and the worst in elderly.Conclusion Age factors influence the effect of surgical treatment of adrenal hyperplasia hypertension.