单一羰基溶剂体系的茴脑臭氧化反应

Ozonolysis of Anethole in Single Solvent with Carbonyl Group

以茴脑为原料,臭氧化法制备茴香醛。通过实验筛选出茴香醛产率较好的含羰基单一溶剂体系,并考察了溶剂种类、溶剂用量、臭氧流量和反应时间对反应结果的影响。优化的工艺条件为:乙酸乙酯或丙酮为溶剂,m(茴脑)∶m(溶剂)=1∶3,臭氧流量0.06 m3/h,反应时间80 min,在该条件下,茴脑转化率达100%,乙酸乙酯溶剂中茴香醛产率可达73.61%,丙酮溶剂中茴香醛产率可达74.54%。

Anisaldehyde was prepared by the ozonolysis of anethole.By experiment,a single solvent system with carbonyl group was found in which anisaldehyde had a good yield.Meanwhile,the species,the mass of solvent,the flow of ozone and time of the reactivity were investigated.The optimum conditions are as follows：acetic ester or acetone as solvent,the mass ratio of anethole and solvent is 1∶3,the flow of ozone is 0.06 m3/h,the reaction time is 80 min.In this condition,the percent conversion of anethole is 100% and the yield of anisaldehyde is 74.54% in ethyl acetate and 73.61% in acetone.