摘要
目的: 介绍抗癫痫药物的临床应用概况,并评价其疗效,借以指导临床合理使用。方法: 对近期国内外抗癫痫药物关于临床应用的文献进行归纳与分析。结果: 癫痫初始治疗药物的选择非常重要,在用药期间应注意药物的不良反应,抗癫痫药的选择应与疗效、安全性等多方面因素结合。结论: 目前,各临床试验方案的设计与临床实际不完全相符。应遵循循证医学的结果,结合患者的实际情况合理使用抗癫痫药物,方能制定出个体化的最佳用药方案。
Objective. Introduce the clinical application of anti-epileptic drugs, and evaluate their efficacy, in order to guide the rational drug use. Motlaods. Sum up and analyze the recent domestic and foreign literature for antiepileptic drugs on the clinical application. Results. The initial choice of anti-epileptic drugs is very important. Physicians and pharmacists should pay attention to the adverse reactions. The choice of anti-epileptic drugs should be combined with efficacy, safety and so on. Conclusions Currently, clinical trial design and clinical practice are not fully compatible. According to evidence-based medicine, combined with the actual situation of patients, physicians and pharmacists could develop the best individualized medication program.
出处
《药品评价》
CAS
2010年第6期34-37,共4页
Drug Evaluation
关键词
抗癫痫药物
临床评价
不良反应
特殊人群
临床试验
Anti-epileptic drugs
Clinical evaluation
Adverse reaction
Special populations
Clinical trial