人血白蛋白278例临床应用调查与分析

Analysis of the Clinical Application of Human Serum Albumin in 278 Inpatients

目的:分析我院人血白蛋白的临床应用情况,促进其合理应用。方法:利用美康合理用药临床药学工作站,收集2009年4～6月我院9个内科科室和4个外科科室共278例人血白蛋白使用病例,采用Excel 2003对其年龄、科室、疾病种类等用药情况进行统计分析。结果:278例患者中,外科用量大于内科,以肝胆外科分布最多,占总例数的22.30%,其次为消化内科(14.75%)、心血管外科(11.87%)、普外科(10.79%);个人用药量多为10～20g;主要用于肿瘤、癌症(82例)、心脏疾病(36例)及骨关节疾病(23例)等重症患者;使用前患者血清白蛋白浓度主要集中在26～35 g·L^(-1)范围内。结论:我院人血白蛋白的临床应用基本合理,但还存在一些使用误区,应本着有效、安全、经济的合理用药原则,严格掌握白蛋白的适应证,促进人血白蛋白的合理应用。

Objective： To analyze the clinical application of human serum albumin in our hospital in order to promote its reasonable use. Method： 278 inpatients using human serum albumin in 9 medical departments and 4 surgery departments of our hospital from April to June 2009 were collected by Meikang clinical pharmacy workstation. The data were statistically analyzed by Excell 2003 according to the age, clinical department, kind of disease and so on. Result： Among the 278 inpatients, the surgery patients used more dosages than the internal medical patients did. Most dosages were used in the liver and gall surgery （22. 30% ） ,then digestion department （ 14. 75% ） ,cardiovascular surgery （ 11.87% ） and general surgery （10. 79% ） in turn. Human serum albumin was mainly used for critical patients such as cancer （82 cases） ,heart disease （36 cases）, bone and joint diseases （23 cases）, etc. with a common individual consumption quantity ranged froml0g to20g. And most of them had a baseline serum albumin level at 26 -35g · L^-1 before using human serum albumin. Conclusion： The application of human serum albumin in our hospital was relatively reasonable. But there were some mistaken applications yet. Only through adhering to the principle of effective, safe, economical and rational use of drugs, and strictly controlling the indication of human serum albumin can a reasonable application of human serum albumin be a- chieved.