期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

腔静脉肌袖Cx40/Cx43与心房颤动的相关研究进展 被引量：1

下载PDF
导出
摘要 腔静脉肌袖内肌纤维走行紊乱,厚薄不均及肌纤维的不连续性都促成了心律失常的发生。腔静脉肌袖内缝隙连接蛋白表达丰富,其中Cx43表达浓度较高,Cx40表达浓度较低,且具有非典型分布,这为心房颤动发生提供了解剖学基础。心房颤动促进腔静脉内缝隙连接蛋白的重构,而其重构又促进了房颤的维持。
作者 凌云 钟国强
机构地区 广西医科大学第一附属医院心内科广西心血管病研究所
出处 《岭南心血管病杂志》 2010年第1期76-78,共3页 South China Journal of Cardiovascular Diseases
基金 广西科学基金资助项目(项目编号:桂科回0575014) 广西医疗卫生重点课题(项目编号:桂卫重200633)
关键词 心房颤动 腔静脉 缝隙连接蛋白 肌袖
分类号 R541.75 [医药卫生—心血管疾病]
  • 相关文献

参考文献14

  • 1YEH H I,LAI Y J,LEE S H,et al.Heterogeneity of myocardial sleeve morphology and gap junctions in canine superior vena cava[J].Circulation,2001,104(25):3152-3157.
  • 2KHOLOVA I,KAUTZNEB J.Morphology of atrial myocardial extensions into human caval veins:a postmortem study in patients with and without atrial fibrillation[J].Circulation,2004,110(5):483-488.
  • 3TSAI C F,TAI C T,HSIEH M H,et al.Initiation of atrial fibrillation by ectopic beats originating from the superior vena cava:electrophys-iological characteristics and results of radiofrequency ablation[J].Circulation,2000,102(1):67-74.
  • 4LIN W S,TAI C T,HSIEH M H,et al.Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy[J].Circulation,2003,107(25):3176-3183.
  • 5马春梅,刘书旺,李红梅,高巍.无心房颤动患者腔静脉电活动特性的研究[J].中国心脏起搏与心电生理杂志,2006,20(3):213-216. 被引量：4
  • 6HAMABE A,OKUYAMA Y,MIYAUCHI Y.Correlation between anatomy and electrical activation in cannie pulmonary veins[J].Circulation,2003,107(11):1550-1555.
  • 7DAVES L M,RODEFELD M E,GREEN K,et al.Gap junction protein human heart and conduction system[J].Cardiovasc Electrophysiol,1995,6(10pt1):813-822.
  • 8ROHR S.Role of gap junctions in the propagation of the cardiac action potential[J].Cardiovasc Res,2004,62(2):309-322.
  • 9JEFFREY E,SAFFITZ H,LEE KANTER H,et al.Tissue specific determinants of anisotropic conduction velocity in canine atrial and ventrieular myocardium[J].Circ Res,1994,74(6):1065-1070.
  • 10YEH H I,LAI Y J,LEE Y N,et al.Differential expression of connexin43 gap junctions in cardiomyocytes isolated from canine thoracic veins[J].J Histochem Cytochem,2003,51(2):259-266.

二级参考文献30

  • 1杨延宗,黄从新,高连君,刘少稳,杨东辉,林治湖.阵发性心房颤动大静脉电隔离后肌袖内自发电活动的特点[J].中华心律失常学杂志,2004,8(3):146-150. 被引量：20
  • 2刘少稳,杨延宗,王祖禄,夏云龙,高连君,林治湖.起源于上腔静脉阵发性心房颤动的特点和射频导管消融治疗[J].中华心律失常学杂志,2004,8(4):200-206. 被引量：9
  • 3黄俊,覃国辉,马业新.大鼠心肌肥厚过程中信号蛋白Smad3的变化[J].基础医学与临床,2004,24(5):556-559. 被引量：1
  • 4冯惠平,崔炜,单保恩,郝京生,都军,郝玉明.醛固酮降低新生大鼠心肌成纤维细胞iNOS表达和NO含量[J].基础医学与临床,2005,25(2):152-155. 被引量：9
  • 5Dolber PC,Beyer EC,Junker JL,et al.Distribution of gap junctions in dog and rat ventricle studied with a double-label technique.J Mol Cell Cardiol,1992,24:1443-1446.
  • 6Sander V, Emily EW,Rishi A, et al. Tissue structure and connexin expression of canine pulmonary veins. Cardiovasc Res,2002,55:727-738.
  • 7Thomas SA,Schuessler RB,Berul CI,et al.Disparate effects of deficient expression of connexin 43 on atrial and ventricular conduction.Circulation,1998,97:685-691.
  • 8Saffitz JE, Schuessler RB, Yamada KA. Mechanisms of remodeling of gap junction distributions and the development of anatomic substrates of arrhythmias. Cardiovasc Res, 1999,42:309-317.
  • 9Ausma J, Wijffels M, Thone F, et al. Structure changes of atrial myocardium due to sustained atrial fibrillation in the goat. Circulation, 1997, 96: 3157-3169.
  • 10Thomas H, Everett IV, Li H, et al. Electrical, morphological, and ultrastructural remodeling and reverse remodeling in a caine model of chronic atrial fibrillation. Circulation, 2000, 102: 1454-1464.

共引文献9

同被引文献25

  • 1周自强,胡大一,陈捷,张仁汉,李奎宝,赵秀丽.中国心房颤动现状的流行病学研究[J].中华内科杂志,2004,43(7):491-494. 被引量：1398
  • 2SKANES A C, HEALEY J S, CAIRNS J A, et al. Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control[I]. Can Cardiol, 2012, 28 (2): 125-136.
  • 3ROY D, TALAJIC M, NATTEL S, et al. Rhythm control versus rate control for atrial fibrillation and heart failure [ J ]. N Engl J Med, 2008, 358(25): 2667-2677.
  • 4AIZAWA Y, KOHSAKA S, SUZUKI S, et al. Comparison of antiarrhythmics used in patients with paroxysmal atrial fibrillation: subanalysis of J-RHYTHM Study [J]. Circ J, 2010, 74(1): 71-76.
  • 5MANDYAM M C, VEDANTHAM V, SCHEINMAN M M, et al. Alcohol and vagal tone as triggers for paroxysmal atrial fibrillation[J]. Am J Cardiol, 2012, 110(3): 364-368.
  • 6DOBREV D, FRIEDRICH A,VOIGT N, et al. The G protein- gated potassium current I(K, ACh) is constitutively active in patients with chronic atrial fibrillation [J ]. Circulation, 2005, 112 ( 24 ) : 3697 - 3706.
  • 7VOIGT N, MAGUY A, YEH Y H, et al. Changes in IK, ACh single-channel activity with atrial taehycardia remodelling in canine atrial cardiomyocytes [ J ]. Cardiovasc Res, 2008,77 ( 1 ) : 35-43.
  • 8MCKINNON L A, ROSOFF M, HAMILTON S E, et al. Regulation of muscarinic receptor expression and function in cultured cells and in knock-out mice[J]. Life Sci, 1997, 60 (13-14) : 1101-1104.
  • 9WANG Z, FERMINI B, NATIEL S. Sustained depolarization- induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K current similar to Kvl.5 cloned channel currents[J]. Circ Res, 1993, 73(6) : 1061-1076.
  • 10CHRIST T, WETTWER E, VOIGT N, et al. Pathology- specific effects of the IKur/Ito/IK, ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation [J]. Br J Phar- macol, 2008, 154(8): 1619-1630.

引证文献1

二级引证文献2

岭南心血管病杂志
2010年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部