检测血浆D-二聚体、FDP、TNT对心肌梗死病人的临床意义

Checkout clinic significance of plasma D-dimer,FDP and TNT in patient with myocardial infarction(AMI)

目的探讨D-二聚体、FDP和TNT在心肌梗死患者病程中的临床意义。方法对32例AMI,28例UAP,22例SAP患者采用乳胶凝集法进行D-二聚体及FDP检测,采用干化学分析法进行TNT检测。结果AMI组与UAP组、SAP组、对照组阳性率比较有显著性差异(P<0.01),SAP组与对照组阳性率比较无显著性差异(P>0.05)。结论血浆D-二聚体可作为急性心肌梗死诊断的参考指标及稳定性心绞痛和不稳定性心绞痛鉴别的参考指标,TNT能对AMI做出早期诊断,并且有特异性,且灵敏度高,其检测迅速、方便,与D-二聚体、FDP联用有助于提高AMI的诊断。

Objective To investigate clinic significance of plasma D-dimer. FDP and TNT in patient with myocardial infarction （AMI） .Methods The plasma D-dimer content and FDP were detetmined by latex agglutination assay, in 32 AMI,28 UAP and 22 SAP,the TNT was detected by dry chemistry method . Results The positive rate of AMI group and UAP group. SAP group, control group have significantly difference （ P 〈 0.01 ）, There are no significant difference between SAP ground and control group. Conclusion Plasma D-dimer content may be considered as an maker for the diagnosis of AMI and has some value in distinction SAP with UAP, TNT can use to diagnose AMI early, which has specificity and high sensitivity, which was detected quickly and conveniently, which was combined with the plasma D-dimer content, FDP can contribute to improve the diagnosis of AMI.