摘要
目的探讨绝经后女性2型糖尿病患者骨密度与冠心病的相关性。方法对176例符合1999年世界卫生组织(WHO)糖尿病诊断标准的绝经后女性2型糖尿病住院患者,应用骨密度仪测定骨密度和T值,根据有无冠心病分为2组,比较骨密度和T值。应用多因素非条件Logistic回归分析的相关性。结果绝经后女性2型糖尿病合并冠心病组的骨密度、T值显著低于不伴有冠心病组(P〈0.01-0.05),调整了年龄、血压、血脂、体重指数、糖尿病病程、绝经时间后,经多因素非条件Logistic回归分析显示骨质疏松与冠心病仍存在显著的相关性(Or=4.465,95%CI:1.650-11.230)。结论绝经后女性2型糖尿病患者骨密度降低可能与冠心病的发生、发展有关。
Objective To assess the association between bone mineral density and coronary heart disease in postmenopausal women with type 2 diabetes.Methods To mensure bone mineral density and T score of 176 postmenopausal women with type 2 diabetes,we divided these women into two groups according to whether they had coronary heart disease or not,and analysed the association between osteoporosis and coronary heart disease.Results Bone mineral density,and T score of patients with coronary heart disease were much lower than those of patients without it.Osteoporosis was related to coronary heart disease by logistic regression analysis,regardless of age,pressure,triglyceride,body mass index,the duration of diabetes,and menopause time.Conclusion The louer of bone mineral density of postmenopausal women with tgpe 2 diabets is related to coronary heart disease.
出处
《中国实用医药》
2010年第11期40-42,共3页
China Practical Medicine
关键词
2型糖尿病
骨密度
冠心病
骨质疏松
Type2 diabetes mellitus
Bone mineral density
Coronary heart disease
Osteoporosis