不规则抗体筛查对临床输血的意义

The Clinical Significance of Irregular Antibodies Screening

目的:探讨不规则抗体的筛查在临床输血中的意义。方法:对2009年5月至10月间本院6300例输血患者做不规则抗体筛查,抗体筛检阳性者做进一步鉴定,分析抗体特异性,总结各抗体出现频率。结果:半年来检测病例6300例,检测出不规则抗体阳性9例,阳性率0.14%,其中抗-D抗体2例,抗-DC抗体1例、抗-E抗体2例,抗-e抗体1例,抗-M抗体3例。还检测出自身抗体3例及高度冷凝集1例。结论:不规则抗体筛选应作为输血前检查之常规,对保障临床用血、预防溶血性输血反应具有极其重要的意义。

Objective： To discuss the meaning of irregular antibodies screen in clinical transfusion. Methods： Irregular antibodies screening was given to 6300 transfusion patients being in our hospital from May to October in 2009 .Further identification was for the positive samples. Then we analyzed their specification. Results： Among the patients screened,9 samples were positive and the positive rate was 0.14 % ,including 2 cases of anti-D antibody, 1 case of anti-DC antibody, 2 cases of anti-E antibody, 1 case of anti-e antibody, 3 cases of autoantibody and 1 case of high condensation. Conclusions： Irregular antibodies screening should be used as the routine examination before transfusion, which is essential to ensuring clinical use of blood and preventing hemolytic transfusion reaction.