早期肠内营养在重症急性胰腺炎中的应用

Early Enteral Nutrition in Patients with Severe Acute Pancreatitis

目的:探讨早期肠内营养在重症急性胰腺炎治疗中的应用价值。方法:将重症急性胰腺炎患者30例分为实验组和对照组,对照组予以常规治疗,实验组在常规治疗的基础上通过鼻空肠管予以早期肠内营养,记录患者WBC、CRP、血淀粉酶、尿淀粉酶恢复时间、白蛋白变化情况、感染率、病死率、并发症发生率、住院时间、住院费用等。结果:实验组WBC、CRP、血淀粉酶、尿淀粉酶恢复时间较对照组明显低,有显著性差异(P<0.05);实验组血清白蛋白升高较对照组明显高,有显著性差异(P<0.05);实验组感染率、病死率、并发症发生率较对照组明显低,但无显著差别(P>0.05);实验组住院时间、住院费用较对照组低,有显著性差异(P<0.05)。结论:早期肠内营养可以改善急性重症胰腺炎营养状况,缩短病程、减低感染率、病死率、并发症发生率、住院时间及住院费用。

Objective： To evaluate the efficacy 0f early enteral nutrition in patients with severe pancreatitis. Method： 30 patients with SAP were randomlv divided into two groups, the experimentation group and the comparison group, the comparison group was given conventional therapy, the experimentation group entera1 nutrition by nasogastric feeding, We measured the recovery time of laboratory parameters[white blood cel1 count（WBC）,C-reactive protein（CRP）,serum amylase and urine amylase],serum albumin, the infection rate, the death rate,the complication rate, length of stay and cost of hospitalization. Result： Recovery time of 1aboratory parameters in the experimentation group was significantly shorter than that in the comparison group （P〈0、05）. The infection rate, the death rate,the complication rate in the experimentation group was significantly shorter than that in the comparison group but was comparable （P〉0.05）. length of stay and cost of hospitalization in the experimentation group were better than those in comparison group （P〈0.05）. Serum albumin in the experimentation group was significantly higher than that in the comparison group （P〈0.05）. Conclusion： Treatment of SAP with early enteral nutrition can improve nutrition,speed up symptom recovery, reduce the infection rate,the death rate,the complication rate,length of stay and cost of hospitalization.