摘要
丙型肝炎病毒(HCV)受体一直是HCV研究的热点之一,除了已经提出的可能受体:CD81、低密度脂蛋白受体、粘多糖、清道夫受体及C型(钙离子依赖型)凝集素DC/L—SIGN等,目前研究者又发现了新的受体claudin、occludin等。本文就上述HCV受体相关分子的研究进展作一综述。
出处
《国际病毒学杂志》
2010年第2期33-37,共5页
International Journal of Virology
基金
国家自然科学基金项目30600021资助
参考文献33
-
1Bartosch B,Cosset F L.Studying HCV cell entry with HCV pseudoparticles (HCVpp).Methods Mol Biol,2009,510:279-293.
-
2Lindenbach B.D.,Evans M.J.,Syder A.J.,et al.Complete replication of hepatitis C virus in cell culture.Science,2005,309(5734):623-626.
-
3Seigneuret,M.Complete predicted three-dimensional structure of the facilitator transmembrane protein and hepatitis C virus receptor CD81:conserved and variable structural domains in the tetraspanin superfamily.Biophys J,2006,90,212-227.
-
4Yi M,Villanueva RA,Thomas DL,et al.From the Cover; Production of infectious genotype la hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells.Proc Natl Acad Sci U S A,2006,103(7):2310-2315.
-
5Akazawa D,Date T,Morikawa K.CD81 expression is important for the permissiveness of huh7 cell clones for heterogeneous hepatitis C virus infection.J Virol,2007,81:5036-5045.
-
6Meuleman P,Hesselgesser J,Paulson M.Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo.Hepatology,2008,48(6):1761-1768.
-
7Brazzoli M.,Bianchi A.,Filippini S..CD81 is a central regulator of cellular events required for hepatitis C virus infection of human hepatocytes.J Virol,2008,82:8316-8329.
-
8Helle F.,Dubuisson J..Hepatitis C virus entry into host cells.Cell Mol Life Sci,2008,65:100-112.
-
9Witteveldt J,Evans M J,Bitzegeio J,et al.CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells.J Gen Virol,2009,90(1):48-58.
-
10Cormier EG,Tsamis F,Kajumo F,et al.CD81 is an entry core-ceptor for hepatitis C virus.Proc Natl Acad Sci USA,2004,101 (19):7270-7274.
同被引文献18
-
1石川,曹以诚,杜正平,卓敏.RNAi抑制丙肝病毒复制的研究进展[J].现代食品科技,2007,23(6):59-62. 被引量:3
-
2Qiu-wei Pan,Scot D Henry,Bob J Scholte,Hugo W Tilanus,Harry LA Janssen,Luc JW van der Laan.New therapeutic opportunities for Hepatitis C based on small RNA[J].World Journal of Gastroenterology,2007,13(33):4431-4436. 被引量:4
-
3Bendelac A,Savage P,Teyton L.The biology of NKT cells.Annu Rev Immunol,2007,25:297-336.
-
4Borg NA,Wun KS,Kjer-Nielsen L,et al.CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature,2007,448:44-49.
-
5Shi MQ,Wang CR,Wei GJ,et al.Experimental African trypanosomiasis:lack of effective CD1d-restricted antigen presentation.Parasite Immunol,2006,28(12):643-647.
-
6Haraguchi K,Takahashi T,Nakahara F,et al.CD1d expression level in tumor cells is an important determinant for anti-tumor immunity by natural killer T cells.Leuk Lymphoma,2006,47:2218-2243.
-
7Kakimi K,Guidotti LG,Koezuka Y,et al.Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J Exp Med,2000,192 (7):921-930.
-
8Jody LB,Leon G,Stephen N,et al.Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection.Immunity,2002,16:583-594.
-
9Guidotti LG,Rochford R,Chung J,et al.Viral clearance without destruction of infected cells during acute HBV infection.Science,1999,284 (5415):825-829.
-
10Ye L,Wang X,Wang S,et al.CD56 + T cells inhibit hepatitis C virus replication in human hepatocytes.Hepatology,2009,49:753-762.
二级引证文献4
-
1邓军霞,张国成,雷迎峰.RNA干扰抗人单股正链RNA病毒感染的研究进展[J].国际病毒学杂志,2012,19(6):283-288. 被引量:3
-
2周清霞.基于自然杀伤T细胞的恩替卡韦治疗乙型病毒性肝炎的疗效评价[J].现代消化及介入诊疗,2013,18(4):201-204. 被引量:1
-
3汪婷婷,江应安,杨丽华,周振东.聚乙二醇干扰素治疗慢性丙型肝炎患者疗效及安全性的Meta分析[J].临床肝胆病杂志,2013,29(11):824-827. 被引量:1
-
4李敏,彭雁忠.自然杀伤T细胞细胞与乙型病毒性肝炎的关联性[J].中国热带医学,2015,15(1):123-125.
-
1黄朝平,唐嗣泉,张建辉.紧密连接蛋白claudin与呼吸道疾病的研究进展[J].医学综述,2013,19(4):580-583.
-
2吴永廉,吴琦,郑建盛.Claudin-1和STAT3在原发性胃癌组织中的表达及临床意义[J].河北联合大学学报(医学版),2013,15(3):333-334. 被引量:1
-
3胡顺金.藻酸双酯钠治疗糖尿病性周围神经病变[J].新药与临床,1993,12(4):211-214. 被引量:14
-
4赵彦军,赵慧娟.血栓通对2型糖尿病高粘滞血症、高脂血症的治疗作用[J].中华今日医学杂志,2003,3(20):34-35. 被引量:1
-
5张久聪,孙利,聂青和.HCV受体及入胞相关分子的研究进展[J].传染病信息,2009,22(4):250-254. 被引量:1
-
6徐守宏.多磺酸粘多糖治疗化疗相关性静脉炎的临床观察[J].医学理论与实践,2010,23(11):1357-1358. 被引量:8
-
7程广霞,杨玉然,张玲.丙型肝炎病毒感染慢性化机制研究进展[J].医学综述,2008,14(24):3740-3743. 被引量:1
-
8吕红波,郎振为.CD209L(L-SIGN)——一种新的SARS冠状病毒受体[J].国外医学(流行病学.传染病学分册),2005,32(1):64-64.
-
9朱震宇,张绍庚,王继涛,孙百军.HCV入胞相关受体的研究进展[J].中华临床医师杂志(电子版),2013,7(11):133-134. 被引量:1
-
10秦源,郭永红,贾战生,张颖.转铁蛋白受体(TfR)在丙型肝炎病毒感染中的作用机制研究进展[J].细胞与分子免疫学杂志,2017,33(2):274-277. 被引量:5