青岛市母婴弓形体感染与异常妊娠的关系

THE RELATION BETWEEN AND ABNORMAL PREGNANCY IN QINGDAO

用间接血凝法和间接免疫荧光法对502名产妇及新生儿弓形体感染情况进行了研究.结果表明,产妇弓形体抗体阳性率为1.59%,8例母亲弓形体抗体阳性的新生儿中,2例抗体阳性,95名母亲抗体阴性的新生儿抗体检测全部阴性.对部分产妇及其新生儿血清行弓形体IgM抗体检测,未见阳性者.此外对105名有不良孕产史妇女血清行弓形体抗体检测,其阳性率同对照组比较也无明显差异.结果提示我市产妇弓形体感染率较低,未见先天性感染者,异常妊娠与弓形体感染无明显关系.

Toxoplasma antibody was detected in 502 puerperal women and some of their offsprings in Qingdao city by using indirect hemag glutination assay (IHA) and indirect immunofluorescence assay (IFA). The positivity rate for IHA was 1.59%. Only two were positive among 103 newborns' cord blood. 8 of them whose mothers were positive in IHA antibody. The specific IgM antibody was also determined in those 8 puerperal women who were positive in IHA antibody and 23 newborns whose morhers were negative in IHA by using indirect immunofluor escence assay. None was positive. Besides, there was no difference between the positive rates of toxoplasma antibody in 105 women who had the history of abnormal pregnancy and in 128 women whose pregnancies were normal. The results showed that the infection rate of toxoplasmosis among pregnant women in our city was low. No evidence was obtained showing toxoplasmosis had a definite pathogenic relationship to the fetal wastages among the subjects in this series. However, the high susceptibility of women to toxoplasmosis was over 98%. It is of real importance for women to prevent toxoplasma infection during pregnancy.