成纤维细胞生长因子受体2在尿道下裂患儿包皮组织中的表达
被引量:2
摘要
尿道下裂是人类泌尿生殖系统常见的先天性疾病,近年来有明显的上升趋势。但是尿道下裂确切的发病机制仍不清楚。目前研究最多的是内分泌激素的调控和其相关的基因突变,但对尿道上皮生长发育相关的因素研究很少。相关报道表明:成纤维细胞生长因子受体2(fibroblast growth factor receptor2,FGFR2)参与了尿道上皮的生长发育,FG—FR2和尿道上皮生长、发育相关,FGFR2的功能研究有助于揭示尿道下裂发生的机制。
出处
《中华小儿外科杂志》
CSCD
北大核心
2010年第3期226-228,共3页
Chinese Journal of Pediatric Surgery
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