期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

血管再狭窄基因治疗的研究现状 被引量：1

下载PDF
导出
摘要 自体静脉移植术、球囊导管扩张成形术和/域血管腔内支架术,是目前最常用的动脉重建方法,但术后再狭窄的发生率达30%～50%.近年有关内膜增生导致再狭窄的机理研究不断深入,基因治疗防治再狭窄的实验研究已取得令人关注的进展.
作者 张柏根 施娅雪
机构地区 上海第二医科大学附属仁济医院血管外科
出处 《外科理论与实践》 1998年第4期197-199,共3页 Journal of Surgery Concepts & Practice
关键词 血管再狭窄 基因治疗 动脉重建
分类号 R654.305 [医药卫生—外科学]
  • 相关文献

参考文献10

  • 1Feldman LJ, Tahlil O, Steg G, et al. Perspectives of arterial gene therapy for the prevention of rest. enosis, Cardiovasc Res, 1996, 32: 194.
  • 2Mann MJ. Genetic engineering of vein grafts resistant to atherosclerosis. Proc Natl Acad Sci USA,1995. 92: 4502.
  • 3边杰芳.反义技术治疗自体移植静脉再狭窄的研究[J].外科理论与实践,1998,3(1):52-54. 被引量：2
  • 4Morishita R, Gibbons GH, Horiuchi M, et al. Agene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc Natl Acad Sci USA,1995, 92: 5855.
  • 5Chang MW, Barr E, Lu MM, et el. Adenovirus-mediated over. expression of the cyclin/cyclin-depend-ent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J Clin Invest 1995, 96: 2260.
  • 6Gerard RD, Collen D. Adenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis.Cardiovasc Res. 1997, 35: 451.
  • 7Isner JM, Walsh K, Rosenfield K, et al. Clinical protocol: arterial gene therapy for restenosis. Hum Gene Ther, 1996, 7: 989.
  • 8Zoldhelyi P, Mcnatt J, Xu XM, et al. Prevention of arterial thrombosis by adenovirus-mediated transfer of cyclooxygenasc gene. Circulation, 1996, 93: 10.
  • 9Brieger D, Topol E. Local drug delivery systems and prevention of restenosis. Cardiovasc Res, 1997,35: 405.
  • 10Nabel EG: Gene therapy for cardiovascular disease.Circulation, 1995, 91: 541.

二级参考文献20

  • 1Mann MJ, Gibbons GH, Kernoff RS, et al. Genetic engineering of vein grafts resistant to atherosclerosis. Proc Natl Acad Sci USA, 1995, 92(10): 4502.
  • 2Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature. 1993, 362: 801.
  • 3Sarkar R, Meinberg EG, Stanley JC, et al. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscule cell. Circ Res, 1996, 79:225.
  • 4Simons M, Edelman ER. Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimal hyperplasia in a rat carotid artery injury model. J Clin Invest. 1994. 93:2351.
  • 5Villa AE, Guzman LA, Poptie EJ, et al. Effects of antisense c-myb oligonucleotides on vascular smooth muscle cell proliferation and response to vessel wall injury. Circ Res, 1995. 76: 505.
  • 6Edelman ER, Simons M, Sirois MG, et al. C-myc in vasculoproliferative disease. Circ Res, 1995, 76:176.
  • 7Abe J, Zhou W, Taguchi J, et al. Suppression of neointimal smooth muscle cell accumulation in vivo by antisense CDC2 and CDK2 oligonucleotides in rat carotid artery. Biochem Biophys Res Commun, 1994, 198: 16.
  • 8Simons M, Rosenberg RD. Antisense nonmuscle myosin heavy chain and c-myb oligonucleotides suppress smooth muslce cell proliferation in vitro.Cite Res. 1992.70: 835.
  • 9Simons M, Edelman ER, Dekeyser JL, et al.Antisense c-myb oligonucleotides inhibit arterial smooth m~scle cell accumulation in vivo. Nature,1,992, 359: 67.
  • 10Kasahara N. Dozy AM, Kan YW. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science, 1994, 266: 1373.

共引文献1

同被引文献1

引证文献1

二级引证文献2

外科理论与实践
1998年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部