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腹腔温热化疗的临床意义及其对机体生理功能的影响 被引量:27

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摘要 进展期胃肠道癌肿的腹膜播散性转移是外科治疗中十分棘手的问题.由于癌细胞侵及浆膜外层后脱落;或手术过程中癌细胞随血液、淋巴液或胃肠液溢入腹腔内;且有解剖区域纤维素渗出隔离层的形成及术后患者免疫功能减弱等因素均促进了腹膜癌细胞种植、转移的过程.近十余年的研究表明腹膜转移已成为胃肠道癌肿术后最常见的复发类型与致死原因.即使施行扩大的淋巴结清扫术或术后全身性辅助化疗仍未能有效地防治术后腹膜转移与复发,以致影响整体疗效的进一步提高.
作者 李琛
出处 《外科理论与实践》 1998年第1期48-51,共4页 Journal of Surgery Concepts & Practice
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  • 1朱正纲,尹浩然,林言箴.胃肠道癌术后腹腔内温热灌注疗法的临床意义[J].普外临床,1995,10(2):73-75. 被引量:15
  • 2Sugarbaker PH, Jablonski KA. Prognosis features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy. Ann Surg, 1995, 221: 124.
  • 3Sugarbaker PH, Averback AM, Jacquet D, et al.Hyperthermic intraoperative intraperitoneal chemotherapy with mitomycin C. Onoclogy, 1997,Surgical technology international, v. 245.
  • 4Yonemura Y, Fujimura T, Mishimura G, et al.Effects of intraoperative chemohyperthermia in patients with gastric cancer with peritoneal dissemination. Surcgery, 1996, 119: 437.
  • 5Fujimoto S, Makoto T, Endoh F, et al. Prevention of peritoneal recurrence in gastric cancer by the chemohyperthermic peritoneal perfusion. First International Gastric Cancer Congress. Kyoto, 1995:1655.
  • 6Los G, van Vugt MJH, Pinedo HM. Response of peritoneal solid tumors after intraperitoneal chemohyperthermia treatment with cisplatin or carboplatin. Br J Cancer, 1989, 69: 235.
  • 7Hananel N, Gordon PH, FRCSC, et al. Effect of 5-flurouracil and leucovorin on the integrity of colonic anastomoses in the rats. Dis Colon Rectum, 1995, 38: 886.
  • 8Kern W, Braess J, Samel S, et al. Parmacokinetics of cisplatin and its impact on nephrotoxicity during intraoperative hyperthermic peritoneal lavrage in patients with locally advanced gastric cancer. 2nd International Gastric Cancer Congress, 1997: 1387.
  • 9Fujimura T, Yonemura Y, Muraoka K, et al.Continuous hyperthermic peritoneal perfusion for the prevention of peritoneal recurrence of gastriccancer. World J Surg, 1994, 18: 150.
  • 10Giny FN, Carry PY, Sayag AC, et al. Tolerance of intraperitoneal chemohyperthermia with MMC: In vivo study in dogs. Int J Hyperthermia,1992. 8: 659.

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