胆固醇与胆结石的关系

Relationship between blood total cholesterol and gallstones

目的:探讨胆固醇与胆结石的关系.方法:对某高校3905名教职员工进行健康检查,采用彩超进行肝胆检查,全自动生化分析仪进行血总胆固醇测定,分析他们二者的关系.结果:3905名教职员工健康检查发现胆结石189例,其中胆固醇增高(>5.17mmol/L)68例(35.98%),胆固醇正常偏高(4.67-5.16mmol/L)40例(21.16%),胆固醇正常(<5.17mmol/L)81例(42.86%),胆固醇正常偏高和增高与胆固醇正常相比,其胆结石发病率明显增高(均P<0.01).结论:胆结石与高胆固醇增高有一定关系,在胆结石保守治疗时,应注意降低胆固醇.

AIM： To investigate the relationship between blood total cholesterol and gallstones. METHODS： The teaching and administrative staff （n = 3905） at a university who underwent a routine physical examination were included in the study. Gallstones were detected by color ultrasound, and blood total cholesterol was determined using an automatic biochemical analyzer. RESULTS： A total of 189 cases of gallstones were screened, of which 68 （35.98%） had mark- edly elevated cholesterol levels （ 5.17 mmol/L）, 40 （21.16%） had slightly elevated cholesterol levels （4.67-5.16 mmol/L）, and 81 cases （42.86%） had normal cholesterol levels （ 5.17 mmol/L）. The prevalence of gallstones in subjects with elevated cholesterol levels was significantly higher than that in subjects with normal cholesterol levels （P 0.01）. CONCLUSION： High cholesterol may be associated with the development of gallstones. Duringconservative therapy of gallstones, lowering cholesterol should be considered.