复发缺血事件与心肌梗死后心源性猝死相关性质疑

Query of the relationship between recurrent ischemia and sudden cardiac death after myocardial infarction

心肌梗死是严重威胁人类健康的心血管疾病。心肌梗死存活者有很高的心源性猝死风险。2008年11月,《美国医学会杂志》(JAMA)发表的题为"心肌梗死后心源性猝死"的文章,探讨了人群中心肌梗死后心源性猝死的发生率及其与复发缺血事件以及心力衰竭的相关性。我们对该项研究的几处试验设计细节提出了质疑,认为心肌梗死后心源性猝死与复发缺血事件无关的结论值得商榷。

Myocardial infarction does great harm to human healthiness. The myocardial infarction survivors are at high risk for sudden cardiac death. There was an article named ＂Sudden Death After Myocardial Infarction＂ on the Journal of American Medical Association in November 2008, which evaluated the risk of sudden cardiac death after myocardial infarction in community and the impact of recurrent ischemia and heart failure on sudden cardiac death. We queried some details of the trial design, and we thought the conclusion that sudden cardiac death is not associated with recurrent ischemia was doubtable.