仰卧位密切相关的阻塞性睡眠呼吸暂停低通气综合征患者的临床特征分析

Clinical features of OSAHS closely associated with supine position

目的探讨仰卧位密切相关的阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopneasyndrome,OSAHS)患者的临床特征。方法回顾在我院进行多导睡眠监测的105例OSAHS患者,分成两组:一组为体位睡眠组(positional patients,PP),另一组为非体位睡眠组(nonpositional patients,NPP),比较两组在年龄、体块指数(body mass index,BMI)、病情严重程度的差别。结果PP组与NPP组比较,年龄[(40.4±10.5)岁versus(37.0±10.6)岁]及BMI[(28.2±3.8)kg/m2versus(29.1±3.0)kg/m2]之间差异无显著性;AHI之间[(36.8±25.4)次/h versus(51.2±29.0)次/h]差异具有显著性。轻中度OSAHS患者仰卧位时和非仰卧位时AHI[(23.9±13.8)次/h versus(12.4±10.1)次/h]比较,差异具有非常显著性。结论PP组多为轻中度患者;对于轻中度患者,体位治疗是不容忽视的治疗方式。

OBJECTIVE To study the clinical features of OSAHS patients closely associated with supine position. METHODS The clinical data of 105 patients with OSAHS diagnosed by overnight polysomnography（PSG）were retrospectively studied. The patients were divided in two groups： the positional patients（PP）group, those patients who had a apnea-hypopnea index（AHI） that was at least two times higher than the lateral AHI, and the non-positional patients（NPP）group, those patients in whom the AHI in the supine position was two times less than that in the lateral position, and the two groups were compared with age, BMI and the severity of OSAHS. RESULTS The difference of age and BMI were not significant between the two groups[（40.4±10.5）year versus（37.0±10.6） year,（28.2±3.8）kg/m2 versus（29.1±3.0）kg/m2]. There was significantly different in AHI between two groups[（36.8±25.4）/h versus （51.2±29.0）/h ]. AHIsupine and AHInot-supine was significantly different in mild and moderate OSAHS patients [（23.9±13.8） /h versus（12.4±10.1）/h ]. CONCLUSION Mild and moderate OSAHS patients are mainly PP. Positional therapy should play an important role in treatment of mild and moderate patients.