孕11～13^(+6)周胎儿颈项透明层厚度的超声测量

Ultrasonic measurement of fetal nuchal translucency at 11～13^(+6) weeks

目的分析孕11～13^(+6)周正常胎儿颈项透明层(NT)厚度及其与头臀径的关系。方法选择孕11～13^(+6)周头臀径为45～84 mm的正常胎儿3224例,超声测量胎儿NT厚度和头臀径,并对头臀径与颈NT厚度进行相关性研究。结果胎儿NT厚度随着头臀径的增加而增厚;中位数预测值从头臀径为45 mm时的0.9 mm至头臀径为84 mm时的1.7 mm。结论孕11～13^(+6)周正常胎儿NT厚度的参考值范围为早孕期胎儿染色体异常和其他先天性异常的筛查提供了帮助。

Objective To analyze the relationship between the nuchal translucency （NT） thickness and crown-rump length （CRL） in normal fetus at 11 - 13 ^＋6 weeks. Methods Three thousand two hundred and twenty - four normal fetus with 45 -84 mm CRL at 11 - 13^ ＋6 weeks were enrolled in this study, then their NT thickness and CRL were measured by ultrasound, then the relationship between NT thickness and CRL was analyzed. Results The NT thickness was increased with increasing CRL, The NT thickness increased from 0.9 mm when the CRL is 45 mm to 1.7 mm when the CRL is 84 mm. Conclusion The data of normal fetal NT thickness at 11 - 13 ^＋6 weeks provides the help for screening chromosomal aberrations and other congenital abnormalities in the first trimester.