人ZEBl基因RNA干扰慢病毒载体的构建及鉴定
被引量:1
摘要
上皮细胞-间充质转化(EMT)与恶性肿瘤的侵袭与转移密切相关。锌指增强子结合蛋白1(ZEB1)是目前发现的最强的EMT诱导因子,与肿瘤的恶性进展相关。为进行ZEB1与肝癌关系和基因治疗的研究,本实验构建靶向ZEB1基因的表达RNA干扰的慢病毒表达载体。
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2010年第4期500-500,共1页
Chinese Journal of Experimental Surgery
基金
厦门市科技局资助项目(3502-Z20084010)
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