摘要
目的:探讨血清绒毛膜促性腺激素、孕酮水平与复发性流产患者早期妊娠流产的相关性。方法:对既往无自然流产史、曾有复发性流产史、难免流产孕妇(孕龄6～11周)各30例分别行血清绒毛膜促性腺激素、孕酮检测。结果:β-HCG诊断难免流产的敏感性、特异性、阳性预测值、阴性预测值分别为100%、50%、50%、100%,孕酮则为25%、78%、36%、67%。结论:β-HCG是预测复发性流产患者再次妊娠结局的一个有价值生化指标。
Objective： To predict pregnancy outcome by studying the relation between serum β- HCG and progesterone and the occurrence of miscarriage in the first trimester,in cases with history of recurrent preg- nancy loss. Methods： Serum β - HCG and progesterone levels in 30 pregnant women with history of recurrent pregnancy loss were compared to 30 pregnant women with no history of abortion, and to another group of 30 women who failed to complete the 1st trimester of pregnancy during the study. Result：Serumβ - HCG showed a sensitivity of 100% ,a specificity of 50% ,a PPV of 50% and a NPV of 100%. Serum progesterone showed a sensitivity of 25%, aspecificity of 78%,aPPV of 36% and a NPV of 67%. Conclusion： β -HCG is 100% sensitive with a 50% NPV as a single serum measurement for the prediction of pregnancy outcome.
