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苏拉明对人肝癌在裸鼠体内生长和转移的抑制作用 被引量:2

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摘要 目的 观察肿瘤血管形成制苏拉明对人肝癌在裸鼠体内生长和转移的抑制作用。方法 选用原位接种人肝癌裸鼠转移模型,苏拉明按每次60mg/kg腹腔注射6次,治疗4周后处死并解剖动物,同时肺和肿瘤组织切片免疫组化检测。结果 治疗组肿瘤明显小于对照组,肿瘤肝内播散率,肺转移率和肿瘤组织血管密度治疗组小于对照组。结论 苏拉明可抑制人肝癌在裸鼠体内的生长,转移和血管形成。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 1998年第1期3-4,F003,共3页 Chinese Journal of Experimental Surgery
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参考文献1

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