卵巢环状小管性索瘤6例临床病理分析

Ovarian sex cord tumor with annular tubules: A report of six cases with clinical and pathological analysis

目的：探讨卵巢环状小管性索瘤良恶性区别的标准。方法：对６例卵巢环状小管性索瘤，良性４例，恶性２例，进行临床病理观察，ＡｇＮＯＲ计数及术后随访。结果：恶性者瘤细胞有轻至中度异型性，且见到分裂象，单纯性和复合性小管减少，伴有梁状或弥漫性颗粒细胞瘤样成分。临床随访转移在术后５年以上。结论：此瘤是一种真性肿瘤，可分为单纯型、颗粒细胞为主型和支持细胞为主型。

Purpose To study the differentiation between the benign and malignant ovarian sex cord tumor with annular tubules. Methods Six cases of sex cord tumor with annular tubules, of which four were benign, the other two were malignant, were studied by clinical pathological observation, AgNOR count and clinical follow up. Results The malignant one had mild or moderate cellulas atypia and mitosis, simple and combined tubules decreased with trabecular and diffuse granular cell tumor like pattern. Metastasis was founded 5 years after operation. Conclusion It is concluded that the lesion is a true tumor and is classified into simple, granular cell predominance and sertoli cell predominance. The diagnostic standards of the malignant tumor were presented.