辛伐他汀对心肌梗死患者血脂水平的影响及疗效观察

The efficacy of the impact Effect of atorvastatin on lipid levels in patients with myocardial infarction and clinical

目的：探讨辛伐他汀对心肌梗死患者血脂水平的影响及疗效观察。方法：50例急性心肌梗死患者随机分为治疗组（常规治加辛伐他汀20mg）30例和对照组（常规治疗）20例，观察两组的疗效及血脂水平的变化，及心血管事件的发生率。结果：两组患者治疗后TC、TG、LDL、ET-1和NO水平与治疗前比较，差异有显著性（P〈0．05）。治疗组的心血管事件，人心源性死亡、心肌梗死、心绞痛再入院的总发生率16．7％，明显低于对照组的总发生率60．0％，经统计学分析，差异有统计学意义（P〈0．05）。结论：辛伐他汀不仅能降低TC、TG、LDL，延缓疾病的进展，而且能降低梗死后心血管事件的发生率。

Objective To investigate the effect of atorvastatin on lipid levels in patients with myocardial infarction and clinical efficacy of the impact. Methods 60 patients with acute myocardial infarction were randomly divided into treatment group （conventional rule Jia Etuo Simvastatin 20mg） and the control group （conventional treatment） and 30 cases were observed in efficacy and changes in lipid levels and the incidence of cardiovascular events. Results After treatment, both groups TC, TG, LDL, ET-1 and NO levels compared with those before treatment, the difference was significant （P〈0.05）. Treatment group, cardiovascular events, into the cardiac death, myocardial infarction, angina pectoris re-admission of the overall incidence of 16.7%,Significantly lower than the control group, the overall incidence of 50.0%, after statistical analysis, the difference was statistically significant （P〈0.05）. Conclusion Atorvastatin can not only reduce TC, TG, LDL, slow progression of the disease, but also to reduce infarction the incidence of cardiovascular events.