丹参调节血管新生及其机制研究进展

Progress on Radix Salviae Miltiorrhiae modulating angiogenesis and its mechanisms

丹参可调节血管新生。本文从细胞水平、器官水平、整体水平回顾了丹参调节血管新生的作用,并从血管内皮生长因子和/或其受体、基质金属蛋白酶、一氧化氮和碱性成纤维细胞生长因子的角度综述了其作用机制。

Radix Salviae Miltiorrhiae can modulate angiogenesis.This paper reviewed these actions on cellular level,organ level and whole organism level.We reviewed their mechanisms on VEGF（vascular endothelial growth factor）and/or its receptors,Matrix metalloproteinases（MMPs）,NO（nitric oxide）and bFGF（basic fibroblast growth factor）.