L-阿拉伯糖对降低高糖高脂喂养小鼠体重增长速率的影响

Effects on reduction of weight increasing rate in rats feeding with high-fat and sucrose diet

将L-阿拉伯糖通过口服的方法配合高糖高脂饲料喂养SPF级昆明雄性小鼠,观察不同剂量L-阿拉伯糖对小鼠增重速率的影响。将100只小鼠随机均分为A、B、C、D、E五组(五组小鼠体重没有显著差异),分别采用高、中、低和零四种剂量水平口服L-阿拉伯糖水溶液1个月,另设E组为空白对照,记录小鼠体重和体长变化。结果表明:L-阿拉伯糖对小鼠的体重增长有剂量依存关系,小剂量(0.5g/kg)即可产生作用,但只有添加量达到一定的浓度后(1.0g/kg),其抑制小鼠体重增长速率作用才有明显效果(P<0.05)。L-阿拉伯糖能有效减缓肥胖小鼠的体重增长速率。

To investigate the effects of different doses L-Arabinose（LA） on reduction of weight increasing rate of rats,100 SPF Kunming rats were fed under high fat and sucrose diets with diffirent doses of L-Arabinose for 1 month.The rats were divided into five groups,A（high LA）,B（mid LA）,C（low LA）,D（no LA） and E（control group）,which initial weight was not significantly different among the groups.The weights were recorded every several days.Results reveal that L-Arabinose has a dose-dependent with weight increasing rate of mice,low-dose（0.5 g/kg） can make a difference,but only add the amount up to a certain concentration （1.0 g/kg）,its inhibitory growth rate of body weight of mice have a significant effect（P0.05）.Conclusion：L-Arabinose can effectively reduce rates of weight gain in obesity rats.