抗幽门螺杆菌治疗再发性腹痛与慢性浅表性胃炎的疗效

Curative Effect of Anti-Helicobacter Pylori Treatment on Recurrent Abdominal Pain and Chronic Superficial Gastritis in Children

目的探讨抗幽门螺杆菌(Hp)治疗再发性腹痛(RAP)和慢性浅表性胃炎(CSG)的疗效及其必要性。方法选择本院符合RAP诊断的患儿118例,其中Hp感染52例;胃镜检查后确诊CSG120例,其中Hp感染58例。分别将其分为3组(Hp阴性组、抗Hp治疗组、未抗Hp治疗组),所有患儿治疗3个月,分别行胃镜检查、Hp检测和临床疗效判断,应用SPSS11.0软件进行统计学分析。结果CSG和RAP的发病与Hp感染与否均无关(Pa>0.05)。RAP抗Hp治疗组治疗前后疗效比较差异有统计学意义(χ2=6.74,P<0.05);CSG抗Hp治疗组治疗前后疗效比较差异有统计学意义(χ2=6.16,P<0.05)。结论CSG和RAP的发病与Hp感染无明确相关性,但CSG和RAP的患儿一旦明确有Hp感染,仍应予Hp根除治疗。

Objective To investigate the curative effect and its necessity of anti-Helicobacter pylori（Hp） treatment on recurrent abdominal pain（RAP）,chronic superficial gastritis（CSG）.Methods One hundred and eighteen cases were diagnosed as RAP,among whom 52 cases were infected with Hp;Gastroscopy confirmed CSG in 120 cases,of whom 58 cases were infected with Hp.They were divided into 3 groups which including Hp-negative group,anti-Hp treatment group and non-anti-Hp treatment group.All children had been treated in 3 months,and then had gastroscopy,Hp testing,and clinical efficacy determination,and the data were analyzed by SPSS 11.0 software.Results There was no correlation between the incidence of CSG,RAP in children and Hp infection（Pa0.05）.There was significant difference of curative effect before and after treatment of children with RAP（χ2=6.74,P0.05） and CSG （χ2= 6.16,P0.05） in anti-Hp treatment group.Conclusions There is no correlation between the incidence of CSG,RAP in children and Hp infection,and they should have Hp eradication therapy once confirmed with Hp infection.